ENSGALG00000010773


Gallus gallus

Features
Gene ID: ENSGALG00000010773
  
Biological name :GREM2
  
Synonyms : GREM2 / gremlin 2, DAN family BMP antagonist
  
Possible biological names infered from orthology : Gremlin-2 / O88273 / Q9H772
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 36304884
Gene end: 36305390
  
Corresponding Affymetrix probe sets: GgaAffx.20149.1.S1_at (Chicken Array)   GgaAffx.6804.1.A1_at (Chicken Array)   GgaAffx.6804.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000062071
NCBI entrez gene - 421507     See in Manteia.
RefSeq - XM_419552
swissprot - A0A1L1RTC7
Ensembl - ENSGALG00000010773
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 grem2aENSDARG00000056057Danio rerio
 grem2bENSDARG00000103092Danio rerio
 GREM2ENSG00000180875Homo sapiens
 Grem2ENSMUSG00000050069Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GREM1 / O73755 / Gremlin-1 / O60565* / O70326* / gremlin 1, DAN family BMP antagonist*ENSGALG0000000972459
NBL1 / neuroblastoma 1, DAN family BMP antagonist / P41271* / Q61477* / Neuroblastoma suppressor of tumorigenicity 1 *ENSGALG0000004029725


Protein motifs (from Interpro)
Interpro ID Name
 IPR004133  DAN
 IPR006207  Cystine knot, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010172 embryonic body morphogenesis IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IEA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IEA
 biological_processGO:0038098 sequestering of BMP from receptor via BMP binding IEA
 biological_processGO:0048263 determination of dorsal identity IEA
 biological_processGO:0060300 regulation of cytokine activity IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0036122 BMP binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
Signaling by BMP


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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