ENSGALG00000011009


Gallus gallus

Features
Gene ID: ENSGALG00000011009
  
Biological name :SCN2A
  
Synonyms : SCN2A / sodium voltage-gated channel alpha subunit 2
  
Possible biological names infered from orthology : Q99250 / sodium channel, voltage-gated, type II, alpha
  
Species: Gallus gallus
  
Chr. number: 7
Strand: -1
Band:
Gene start: 19912741
Gene end: 19968241
  
Corresponding Affymetrix probe sets: Gga.14047.1.S1_at (Chicken Array)   Gga.562.1.S1_s_at (Chicken Array)   GgaAffx.20680.1.S1_s_at (Chicken Array)   GgaAffx.23424.1.S1_at (Chicken Array)   GgaAffx.6995.1.S1_s_at (Chicken Array)   GgaAffx.6995.3.S1_at (Chicken Array)   GgaAffx.6995.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000017912
NCBI entrez gene - 395945     See in Manteia.
RefSeq - XM_015289635
RefSeq - NM_001293281
RefSeq - XM_015289633
RefSeq - XM_015289634
RefSeq - XM_004942786
RefSeq - XM_004942787
RefSeq - XM_015289631
RefSeq - XM_015289632
RefSeq Peptide - NP_001280210
swissprot - E1BQT2
Ensembl - ENSGALG00000011009
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scn1aENSDARG00000086819Danio rerio
 scn1labENSDARG00000062744Danio rerio
 SCN2AENSG00000136531Homo sapiens
 Scn2aENSMUSG00000075318Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SCN1A / sodium voltage-gated channel alpha subunit 1 / A2APX8* / P35498* / Sodium channel protein type 1 subunit alpha *ENSGALG0000001094388
SCN3A / sodium voltage-gated channel alpha subunit 3 / Q9NY46* / sodium channel, voltage-gated, type III, alpha*ENSGALG0000001104088
SCN9A / sodium channel protein type 9 subunit alpha / SCN7A* / Q62205* / Q15858* / Q01118* / sodium voltage-gated channel alpha subunit 7* / sodium voltage-gated channel alpha subunit 9*ENSGALG0000002779381
SCN8A / sodium voltage-gated channel alpha subunit 8 / Q9UQD0* / sodium channel, voltage-gated, type VIII, alpha*ENSGALG0000004372876
SCN5A / Gallus gallus sodium voltage-gated channel alpha subunit 5 (SCN5A), mRNA. / Q9JJV9* / Q14524* / Sodium channel protein type 5 subunit alpha * / sodium voltage-gated channel alpha subunit 5*ENSGALG0000000611266
SCN4A / Gallus gallus sodium voltage-gated channel alpha subunit 4 (SCN4A), mRNA. / P35499* / sodium voltage-gated channel alpha subunit 4* / sodium channel, voltage-gated, type IV, alpha*ENSGALG0000003442761
ENSGALG0000000607258
SCN11A / Gallus gallus sodium voltage-gated channel alpha subunit 11 (SCN11A), mRNA. / Q9UI33* / Q9R053* / Sodium channel protein type 11 subunit alpha * / sodium voltage-gated channel alph...ENSGALG0000002770250
CACNA1G / calcium voltage-gated channel subunit alpha1 G / O43497* / calcium channel, voltage-dependent, T type, alpha 1G subunit*ENSGALG0000000762324
CACNA1I / calcium voltage-gated channel subunit alpha1 I / Q9P0X4* / calcium channel, voltage-dependent, alpha 1I subunit*ENSGALG0000003505123
CACNA1H / calcium voltage-gated channel subunit alpha1 H / O95180* / voltage-dependent T-type calcium channel subunit alpha-1H isoform 2 *ENSGALG0000000521518


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001696  Voltage gated sodium channel, alpha subunit
 IPR005821  Ion transport domain
 IPR010526  Sodium ion transport-associated
 IPR024583  Voltage-gated Na+ ion channel, cytoplasmic domain
 IPR027359  Voltage-dependent channel domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress IEA
 biological_processGO:0019228 neuronal action potential IBA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0051402 neuron apoptotic process IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0086010 membrane depolarization during action potential IBA
 cellular_componentGO:0001518 voltage-gated sodium channel complex IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0014704 intercalated disc IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030315 T-tubule IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0033270 paranode region of axon IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005248 voltage-gated sodium channel activity IBA
 molecular_functionGO:0005272 sodium channel activity IEA


Pathways (from Reactome)
Pathway description
Phase 0 - rapid depolarisation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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