ENSGALG00000011297


Gallus gallus

Features
Gene ID: ENSGALG00000011297
  
Biological name :CRADD
  
Synonyms : CASP2 and RIPK1 domain containing adaptor with death domain / CRADD
  
Possible biological names infered from orthology : Mus musculus CASP2 and RIPK1 domain containing adaptor with death domain (Cradd), transcript variant 3, mRNA. / O88843 / P78560
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 44903758
Gene end: 44979576
  
Corresponding Affymetrix probe sets: GgaAffx.7181.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000018406
NCBI entrez gene - 417900     See in Manteia.
RefSeq - NM_001030748
RefSeq - XM_015283756
RefSeq Peptide - NP_001025919
swissprot - Q5F3I3
Ensembl - ENSGALG00000011297
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 craddENSDARG00000028192Danio rerio
 CRADDENSG00000169372Homo sapiens
 CraddENSMUSG00000045867Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000488  Death domain
 IPR001315  CARD domain
 IPR011029  Death-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0071260 cellular response to mechanical stimulus IEA
 biological_processGO:2001235 positive regulation of apoptotic signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0002020 protease binding IEA
 molecular_functionGO:0030674 protein binding, bridging IEA
 molecular_functionGO:0070513 death domain binding IEA


Pathways (from Reactome)
Pathway description
TP53 Regulates Transcription of Caspase Activators and Caspases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000011297 CRADD / CASP2 and RIPK1 domain containing adaptor with death domain / O88843* / P78560* / Mus musculus CASP2 and RIPK1 domain containing adaptor with death domain (Cradd), transcript varian...  / complex / reaction
 ENSGALG00000014698 CASP2 / caspase-2 / P29594* / P42575* / Caspase-2 Caspase-2 subunit p18 Caspase-2 subunit p13 Caspase-2 subunit p12*  / complex / reaction
 ENSGALG00000040729 PIDD1 / p53-induced death domain protein 1 / Q9ERV7* / Q9HB75* / p53-induced death domain-containing protein 1 *  / complex / reaction






 

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