ENSGALG00000011306


Gallus gallus
filamentDESproteincytoskeletonjunctiondiscbindingheaddna-bindingdomainconservedsitedesminorganizationnucleuscytoplasmcell-cellfasciaadherensintercalatedzneuromuscularsarcolemmacontractilefiberdensebodycardiacmyofibrilstructural

Features
Gene ID: ENSGALG00000011306
  
Biological name :DES
  
Synonyms : DES / desmin
  
Possible biological names infered from orthology : P17661 / P31001
  
Species: Gallus gallus
  
Chr. number: 7
Strand: -1
Band:
Gene start: 22291852
Gene end: 22295615
  
Corresponding Affymetrix probe sets: Gga.535.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000018424
NCBI entrez gene - 395906     See in Manteia.
RefSeq - XM_015290092
swissprot - E1BZ05
Ensembl - ENSGALG00000011306
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 desmaENSDARG00000058656Danio rerio
 desmbENSDARG00000005221Danio rerio
 DESENSG00000175084Homo sapiens
 DesENSMUSG00000026208Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
VIM / vimentin / P08670* / P20152*ENSGALG0000000867761
GFAP / glial fibrillary acidic protein / P03995* / P14136*ENSGALG0000000090951
NEFL / neurofilament light / P07196* / P08551* / Neurofilament light polypeptide *ENSGALG0000000031442
NEFM / neurofilament medium polypeptide / P07197* / neurofilament medium*ENSGALG0000000031741
NEFH / neurofilament heavy / P12036* / P19246* / Neurofilament heavy polypeptide *ENSGALG0000000808534
LMNB2 / lamin-B2 / P21619* / Q03252*ENSGALG0000000047029
LMNB1 / lamin-B1 / P14733* / P20700*ENSGALG0000001469226
LMNA* / P02545* / P48678* / lamin A/C* / Prelamin-A/C Lamin-A/C*ENSGALG0000000608325


Protein motifs (from Interpro)
Interpro ID Name
 IPR001664  Intermediate filament protein
 IPR006821  Intermediate filament head, DNA-binding domain
 IPR018039  Intermediate filament protein, conserved site
 IPR027698  Desmin


Gene Ontology (GO)
cellular component organizationintermediate filament-based processcellular component organizationintermediate filament-based processcellular component organizationintermediate filament-based processcellular component organizationintermediate filament-based processcellular component organizationintermediate filament-based processcellular component organizationintermediate filament-based processcellular component organizationintermediate filament-based processcellular component organizationintermediate filament-based processcellular component organizationintermediate filament-based processcellular component organizationintermediate filament-based processcellular component organizationcellular component organizationintermediate filament-based processintermediate filament-based process
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellorganellesupramolecular complexcell junctionsynapsemembranecellorganellesupramolecular complexcell junctionsynapsemembranecellorganellesupramolecular complexcell junctionsynapsemembranecellorganellesupramolecular complexcell junctionsynapsemembranecellorganellesupramolecular complexcell junctionsynapsemembranecellorganellesupramolecular complexcell junctionsynapsemembranecellorganellesupramolecular complexcell junctionsynapsemembranecellorganellesupramolecular complexcell junctionsynapsemembranecellorganellesupramolecular complexcell junctionsynapsemembranecellorganellesupramolecular complexcell junctionsynapsemembranecellcellorganelleorganellesupramolecular complexsupramolecular complexcell junctioncell junctionsynapsesynapsemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0045109 intermediate filament organization IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005882 intermediate filament IDA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0005916 fascia adherens IEA
 cellular_componentGO:0014704 intercalated disc IEA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0031594 neuromuscular junction IEA
 cellular_componentGO:0042383 sarcolemma IEA
 cellular_componentGO:0043292 contractile fiber IEA
 cellular_componentGO:0045111 intermediate filament cytoskeleton IEA
 cellular_componentGO:0097433 dense body IDA
 cellular_componentGO:0097512 cardiac myofibril IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0008092 cytoskeletal protein binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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