ENSDARG00000058656


Danio rerio

Features
Gene ID: ENSDARG00000058656
  
Biological name :desma
  
Synonyms : desma / desmin a
  
Possible biological names infered from orthology : DES / desmin / P17661 / P31001
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 7515864
Gene end: 7539326
  
Corresponding Affymetrix probe sets: Dr.34.1.S1_at (Zebrafish Array)   NM_130963_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000075991
Ensembl peptide - ENSDARP00000075994
NCBI entrez gene - 30148     See in Manteia.
RefSeq - NM_001328376
RefSeq - NM_130963
RefSeq Peptide - NP_001315305
RefSeq Peptide - NP_571038
swissprot - F1R8W3
swissprot - F1R8W4
ZFIN ID - ZDB-GENE-980526-221
Ensembl - ENSDARG00000058656
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DESENSGALG00000011306Gallus gallus
 DESENSG00000175084Homo sapiens
 DesENSMUSG00000026208Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
desmb / desmin b / DES* / desmin* / P17661* / P31001*ENSDARG0000000522175
vim / vimentin / P08670* / P20152*ENSDARG0000001000853
viml / vimentin like / VIM* / P08670* / vimentin*ENSDARG0000004450152
gfap / glial fibrillary acidic protein / P03995* / P14136*ENSDARG0000002530148
prph / peripherin / P41219*ENSDARG0000002830648
inaa / internexin neuronal intermediate filament protein, alpha a / INA* / Q16352* / P46660* / internexin neuronal intermediate filament protein alpha*ENSDARG0000001186243
inab / internexin neuronal intermediate filament protein, alpha b / INA* / Q16352* / P46660* / internexin neuronal intermediate filament protein alpha*ENSDARG0000005324843
zgc:65851ENSDARG0000001228139
neflb / neurofilament, light polypeptide b / NEFL* / P08551* / P07196* / neurofilament light* / Neurofilament light polypeptide *ENSDARG0000001242638
nefla / neurofilament, light polypeptide a / NEFL* / P08551* / P07196* / neurofilament light* / Neurofilament light polypeptide *ENSDARG0000005756838
nefma / neurofilament, medium polypeptide a / NEFM* / P07197* / neurofilament medium*ENSDARG0000002135135
ngs / notochord granular surfaceENSDARG0000005432135
nefmb / neurofilament, medium polypeptide b / NEFM* / P07197* / neurofilament medium*ENSDARG0000004369734
zgc:172323ENSDARG0000005320134
si:dkey-33c12.3ENSDARG0000005788132
si:dkey-27m7.4ENSDARG0000000314630
lmna / lamin A / P02545* / P48678* / lamin A/C* / Prelamin-A/C Lamin-A/C*ENSDARG0000001341525
lmnb1 / lamin B1 / P14733* / P20700*ENSDARG0000004429925
lmnb2 / lamin B2 / P21619* / Q03252*ENSDARG0000010162425
lmnl3 / lamin L3ENSDARG0000000775124


Protein motifs (from Interpro)
Interpro ID Name
 IPR001664  Intermediate filament protein
 IPR006821  Intermediate filament head, DNA-binding domain
 IPR018039  Intermediate filament protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006936 muscle contraction IGI
 biological_processGO:0007519 skeletal muscle tissue development IMP
 biological_processGO:0007626 locomotory behavior IMP
 biological_processGO:0010882 regulation of cardiac muscle contraction by calcium ion signaling IMP
 biological_processGO:0030239 myofibril assembly IMP
 biological_processGO:0045214 sarcomere organization IMP
 biological_processGO:0055117 regulation of cardiac muscle contraction IMP
 biological_processGO:0060047 heart contraction IMP
 biological_processGO:0060538 skeletal muscle organ development IGI
 cellular_componentGO:0005882 intermediate filament IEA
 cellular_componentGO:0030018 Z disc IDA
 molecular_functionGO:0005198 structural molecule activity IEA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000037 anatomical structure anatomical structure decreased amount , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000114 heart heart edematous , abnormal
heart decreased contractility , abnormal
Show

 ZFA:0000154 sinus venosus sinus venosus increased accumulation blood , abnormal
Show

 ZFA:0000155 somite somite muscle decreased area , abnormal
Show

 ZFA:0001089 myoseptum myoseptum decreased thickness , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
whole organism decreased mobility , abnormal
Show

 ZFA:0001115 trunk trunk curved , abnormal
Show

 ZFA:0005061 ventricular myocardium ventricular myocardium spatial pattern , abnormal
Show

 ZFA:0005145 muscle muscle disorganized , abnormal
muscle contractile fiber spatial pattern , abnormal
Show

 ZFA:0005277 skeletal muscle skeletal muscle refractivity , abnormal
skeletal muscle nucleus circular , abnormal
skeletal muscle sarcomere disorganized , abnormal
skeletal muscle mitochondrial crista decreased amount , abnormal
skeletal muscle sarcoplasmic reticulum dilated , abnormal
Show

 ZFA:0005280 cardiac muscle cardiac muscle Z disc increased width , abnormal
cardiac muscle Z disc disorganized , abnormal
Show

 ZFA:0009114 muscle cell muscle cell vacuole increased amount , abnormal
Show

 ZFA:0009115 skeletal muscle cell skeletal muscle cell decreased size , abnormal
skeletal muscle cell degenerate , abnormal
skeletal muscle cell broken , abnormal
skeletal muscle cell misaligned with skeletal muscle cell , abnormal
skeletal muscle cell structure , ameliorated
skeletal muscle cell broken , ameliorated
skeletal muscle cell alignment skeletal muscle cell , ameliorated
skeletal muscle cell mitochondrion dilated , abnormal
skeletal muscle cell sarcomere disorganized , abnormal
skeletal muscle cell T-tubule bent , abnormal
skeletal muscle cell T-tubule disorganized , abnormal
Show

 ZFA:0009316 cardiac muscle cell cardiac muscle cell sarcomere decreased thickness , abnormal
cardiac muscle cell sarcomere decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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