ENSGALG00000011894


Gallus gallus

Features
Gene ID: ENSGALG00000011894
  
Biological name :CYP2D6
  
Synonyms : CYP2D6
  
Possible biological names infered from orthology : A0A087X1C5 / Cyp2d10 / Cyp2d11 / Cyp2d12 / Cyp2d22 / Cyp2d26 / Cyp2d34 / Cyp2d40 / CYP2D7 / Cyp2d9 / Cytochrome P450 2D10 / Cytochrome P450 2D11 / Cytochrome P450 2D9 / cytochrome P450 family 2 subfamily D member 6 / cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene) / cytochrome P450, family 2, subfamily d, polypeptide 12 / cytochrome P450, family 2, subfamily d, polypeptide 22 / cytochrome P450, family 2, subfamily d, polypeptide 34 / cytochrome P450, family 2, subfamily d, polypeptide 40 / P10635 / P11714 / P24456 / P24457
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 49442475
Gene end: 49451655
  
Corresponding Affymetrix probe sets: Gga.10540.1.A1_at (Chicken Array)   Gga.10540.1.S1_at (Chicken Array)   Gga.13084.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000019386
NCBI entrez gene - 417981     See in Manteia.
RefSeq - NM_001195557
RefSeq Peptide - NP_001182486
swissprot - F1NJG4
Ensembl - ENSGALG00000011894
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYP2D6ENSG00000100197Homo sapiens
 CYP2D7ENSG00000205702Homo sapiens
 Cyp2d12ENSMUSG00000096852Mus musculus
 Cyp2d22ENSMUSG00000061740Mus musculus
 Cyp2d26ENSMUSG00000022445Mus musculus
 Cyp2d34ENSMUSG00000094559Mus musculus
 Cyp2d40ENSMUSG00000068083Mus musculus
 Cyp2d9ENSMUSG00000068086Mus musculus
 P24456ENSMUSG00000094806Mus musculus
 P24457ENSMUSG00000068085Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CYP2J23 / Gallus gallus cytochrome P450, family 2, subfamily J, polypeptide 22 (CYP2J22), mRNA. / Cyp2j6* / Cyp2j7* / Cyp2j8* / Cyp2j9* / P51589* / O54749* / O54750* / CYP2J2* / Cyp2j5* / C...ENSGALG0000001139446
O54749* / CYP2J2* / Cyp2j5* / Cyp2j6* / Cyp2j7* / Cyp2j8* / Cyp2j9* / O54750* / P51589* / Cyp2j11* / Cyp2j12* / Cyp2j13* / Cytochrome P450 2J5 * / Cytochrome P450 2J6 * / cytochrome P450 fa...ENSGALG0000001141341
CYP2AC1 / Gallus gallus cytochrome P450, family 2, subfamily AC, polypeptide 1 (CYP2AC1), mRNA.ENSGALG0000001669041
CYP2R1 / cytochrome P450 family 2 subfamily R member 1 / Q6VVW9* / Q6VVX0* / Vitamin D 25-hydroxylase *ENSGALG0000000605040
CYP2AC2 / Gallus gallus cytochrome P450, family 2, subfamily AC, polypeptide 2 (CYP2AC2), mRNA.ENSGALG0000004663940
CYP2AC7 / Gallus gallus cytochrome P450, family 2, subfamily AC, polypeptide 7 (CYP2AC7), mRNA.ENSGALG0000004419939
CYP2W1* / E9Q816* / Q8TAV3* / Cytochrome P450 2W1 * / cytochrome P450 family 2 subfamily W member 1*ENSGALG0000004503739
CYP2W1* / E9Q816* / Q8TAV3* / Cytochrome P450 2W1 * / cytochrome P450 family 2 subfamily W member 1*ENSGALG0000002123838
CYP2U1 / cytochrome P450 family 2 subfamily U member 1 / Q7Z449* / Q9CX98* / Cytochrome P450 2U1 *ENSGALG0000002790837


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR008069  Cytochrome P450, E-class, group I, CYP2D-like
 IPR017972  Cytochrome P450, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019369 arachidonic acid metabolic process IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008395 steroid hydroxylase activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Fatty acids
Miscellaneous substrates
Xenobiotics
CYP2E1 reactions
Biosynthesis of maresin-like SPMs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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