ENSGALG00000012907


Gallus gallus

Features
Gene ID: ENSGALG00000012907
  
Biological name :MC4R
  
Synonyms : MC4R / melanocortin receptor 4
  
Possible biological names infered from orthology : melanocortin 4 receptor / P32245 / P56450
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 69321367
Gene end: 69323131
  
Corresponding Affymetrix probe sets: GgaAffx.8162.1.A1_at (Chicken Array)   GgaAffx.8162.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000021014
NCBI entrez gene - 428485     See in Manteia.
RefSeq - NM_001031514
RefSeq Peptide - NP_001026685
swissprot - F1NQE8
Ensembl - ENSGALG00000012907
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mc4rENSDARG00000015515Danio rerio
 MC4RENSG00000166603Homo sapiens
 Mc4rENSMUSG00000047259Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MC5R / melanocortin receptor 5 / P33032* / melanocortin 5 receptor*ENSGALG0000003208763
MC3R / melanocortin 3 receptor / P33033* / P41968* / Melanocortin receptor 3 *ENSGALG0000002726059
MC2R / adrenocorticotropic hormone receptor / Q01718* / Q64326* / melanocortin 2 receptor*ENSGALG0000003556945


Protein motifs (from Interpro)
Interpro ID Name
 IPR000155  Melanocortin 4 receptor
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001671  Melanocortin/ACTH receptor
 IPR001908  Melanocortin receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007631 feeding behavior IEA
 biological_processGO:0019222 regulation of metabolic process IEA
 biological_processGO:0030073 insulin secretion IEA
 biological_processGO:0032868 response to insulin IEA
 biological_processGO:0045780 positive regulation of bone resorption IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004977 melanocortin receptor activity IEA
 molecular_functionGO:0004980 melanocyte-stimulating hormone receptor activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0042923 neuropeptide binding IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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