ENSGALG00000013342


Gallus gallus

Features
Gene ID: ENSGALG00000013342
  
Biological name :GBX2
  
Synonyms : GBX2 / homeobox protein GBX-2
  
Possible biological names infered from orthology : gastrulation brain homeobox 2 / P48031 / P52951
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 5187307
Gene end: 5190674
  
Corresponding Affymetrix probe sets: Gga.565.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000052169
Ensembl peptide - ENSGALP00000021739
NCBI entrez gene - 395950     See in Manteia.
RefSeq - NM_205068
RefSeq Peptide - NP_990399
swissprot - F1NF97
swissprot - A0A1D5PH92
Ensembl - ENSGALG00000013342
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gbx2ENSDARG00000002933Danio rerio
 GBX2ENSG00000168505Homo sapiens
 Gbx2ENSMUSG00000034486Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GBX1 / gastrulation brain homeobox 1 / P82976* / Q14549* / Homeobox protein GBX-1 *ENSGALG0000004224137
MNX1 / motor neuron and pancreas homeobox protein 1 / P50219* / Q9QZW9* / motor neuron and pancreas homeobox 1*ENSGALG0000004115420
ENSGALG0000001134919
MEOX2 / homeobox protein MOX-2 / P32443* / P50222* / mesenchyme homeobox 2*ENSGALG0000001079416
MEOX1ENSGALG0000000119115
EVX2 / even-skipped homeobox 2 / P49749* / Q03828* / Homeobox even-skipped homolog protein 2 *ENSGALG0000002076815
NKX1-1 / NK1 homeobox 1 / Q15270* / NK1 transcription factor-related protein 1 *ENSGALG0000003565014
EVX1 / even-skipped homeobox 1 / P23683* / P49640* / Homeobox even-skipped homolog protein 1 *ENSGALG0000003731014
VENTX* / O95231* / VENT homeobox*ENSGALG0000004534312


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa
 IPR031250  Homeobox protein GBX-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001569 branching involved in blood vessel morphogenesis IEA
 biological_processGO:0001755 neural crest cell migration IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0021549 cerebellum development IEA
 biological_processGO:0021555 midbrain-hindbrain boundary morphogenesis IEA
 biological_processGO:0021568 rhombomere 2 development IEA
 biological_processGO:0021794 thalamus development IEA
 biological_processGO:0021884 forebrain neuron development IEA
 biological_processGO:0021930 cerebellar granule cell precursor proliferation IEA
 biological_processGO:0030902 hindbrain development IEA
 biological_processGO:0030917 midbrain-hindbrain boundary development IEA
 biological_processGO:0035239 tube morphogenesis IEA
 biological_processGO:0042472 inner ear morphogenesis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048483 autonomic nervous system development IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000979 RNA polymerase II core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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