ENSGALG00000013348


Gallus gallus

Features
Gene ID: ENSGALG00000013348
  
Biological name :OTUD7B
  
Synonyms : OTUD7B / OTU deubiquitinase 7B
  
Possible biological names infered from orthology : B2RUR8 / OTU domain-containing protein 7B / Q6GQQ9
  
Species: Gallus gallus
  
Chr. number: 25
Strand: 1
Band:
Gene start: 900490
Gene end: 920687
  
Corresponding Affymetrix probe sets: GgaAffx.8497.1.S1_at (Chicken Array)   GgaAffx.8497.2.S1_at (Chicken Array)   GgaAffx.8497.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000021745
NCBI entrez gene - 426041     See in Manteia.
RefSeq - XM_015298347
RefSeq - XM_015298350
RefSeq - XM_015298348
RefSeq - XM_015298349
swissprot - H9L017
Ensembl - ENSGALG00000013348
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 otud7bENSDARG00000017220Danio rerio
 OTUD7BENSG00000264522Homo sapiens
 B2RUR8ENSMUSG00000038495Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OTUD7A / OTU deubiquitinase 7A / Q8R554* / Q8TE49* / OTU domain-containing protein 7A *ENSGALG0000000380259
TNFAIP3 / TNF alpha induced protein 3 / P21580* / Q60769* / tumor necrosis factor, alpha-induced protein 3*ENSGALG0000001386120
ZRANB1 / zinc finger RANBP2-type containing 1 / Q7M760* / Q9UGI0* / zinc finger, RAN-binding domain containing 1*ENSGALG0000003147413


Protein motifs (from Interpro)
Interpro ID Name
 IPR002653  Zinc finger, A20-type
 IPR003323  OTU domain
 IPR033477  Cezanne-2 peptidase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0002385 mucosal immune response IEA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0016579 protein deubiquitination IEA
 biological_processGO:0032717 negative regulation of interleukin-8 production IEA
 biological_processGO:0035871 protein K11-linked deubiquitination IEA
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0070536 protein K63-linked deubiquitination IEA
 biological_processGO:0071108 protein K48-linked deubiquitination IEA
 biological_processGO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process IBA
 biological_processGO:1900181 negative regulation of protein localization to nucleus IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA
 molecular_functionGO:0070530 K63-linked polyubiquitin modification-dependent protein binding IEA
 molecular_functionGO:1990380 Lys48-specific deubiquitinase activity IEA


Pathways (from Reactome)
Pathway description
TNFR1-induced proapoptotic signaling
Regulation of TNFR1 signaling
TNFR1-induced NFkappaB signaling pathway
Ovarian tumor domain proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007932 TRAF6 / TNF receptor associated factor 6 / P70196* / Q9Y4K3*  / complex






 

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