ENSGALG00000014624


Gallus gallus
domainCERS3lagsphingosinesphingolipidbiosyntheticprocessmembranehomeoboxtramclnhomologyhomeobox-likesuperfamilylac-likekeratinocytedifferentiationceramidenucleusendoplasmicreticulumintegralcomponentdnabindingactivitydenovobiosynthesis

Features
Gene ID: ENSGALG00000014624
  
Biological name :CERS3
  
Synonyms : ceramide synthase 3 / CERS3
  
Possible biological names infered from orthology : Q1A3B0 / Q8IU89
  
Species: Gallus gallus
  
Chr. number: 10
Strand: -1
Band:
Gene start: 17297468
Gene end: 17341030
  
Corresponding Affymetrix probe sets: GgaAffx.9268.1.S1_at (Chicken Array)   GgaAffx.9268.2.S1_at (Chicken Array)   GgaAffx.9268.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000057721
Ensembl peptide - ENSGALP00000023528
NCBI entrez gene - 426648     See in Manteia.
RefSeq - XM_424275
RefSeq - XM_015292265
RefSeq - XM_015292266
swissprot - F1N8P2
swissprot - A0A1D5PXM5
Ensembl - ENSGALG00000014624
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cers3aENSDARG00000078541Danio rerio
 cers3bENSDARG00000036337Danio rerio
 CERS3ENSG00000154227Homo sapiens
 Cers3ENSMUSG00000030510Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CERS2 / ceramide synthase 2 / Q924Z4* / Q96G23*ENSGALG0000003914143
CERS4* / Q9D6J1* / Q9HA82* / ceramide synthase 4*ENSGALG0000004335243
CERS5 / ceramide synthase 5 / Q8N5B7* / Q9D6K9*ENSGALG0000003973440
CERS6 / ceramide synthase 6 / Q6ZMG9* / Q8C172*ENSGALG0000001090239
CERS4* / Q9D6J1* / Q9HA82* / ceramide synthase 4*ENSGALG0000000040636
CERS1ENSGALG0000000316022


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR006634  TRAM/LAG1/CLN8 homology domain
 IPR009057  Homeobox-like domain superfamily
 IPR016439  Sphingosine N-acyltransferase Lag1/Lac1-like


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcellular developmental processnitrogen compound menitrogen compound metabolic processbiosynthetic processbiosynthetic processcellular metabolic pcellular metabolic processprimary metabolic prprimary metabolic processorganic substance meorganic substance metabolic processanatomical structureanatomical structure developmentcellular developmentcellular developmental process
organic cyclic compound bindingheterocyclic compound bindingtransferase activityorganic cyclic compound bindingheterocyclic compound bindingtransferase activityorganic cyclic compound bindingheterocyclic compound bindingtransferase activityorganic cyclic compound bindingheterocyclic compound bindingtransferase activityorganic cyclic compound bindingheterocyclic compound bindingtransferase activityorganic cyclic compound bindingheterocyclic compound bindingtransferase activityorganic cyclic compound bindingheterocyclic compound bindingtransferase activityorganic cyclic compound bindingheterocyclic compound bindingtransferase activityorganic cyclic compound bindingheterocyclic compound bindingtransferase activityorganic cyclic compound bindingheterocyclic compound bindingtransferase activityorganic cyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingheterocyclic compound bindingtransferase activitytransferase activity
cellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellcellorganelleorganellemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0030148 sphingolipid biosynthetic process IEA
 biological_processGO:0030216 keratinocyte differentiation IEA
 biological_processGO:0046513 ceramide biosynthetic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0050291 sphingosine N-acyltransferase activity IEA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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