ENSGALG00000015176


Gallus gallus

Features
Gene ID: ENSGALG00000015176
  
Biological name :GNA14
  
Synonyms : GNA14 / G protein subunit alpha 14
  
Possible biological names infered from orthology : guanine nucleotide binding protein, alpha 14 / O95837 / P30677
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 37709882
Gene end: 37769362
  
Corresponding Affymetrix probe sets: GgaAffx.9660.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000024445
NCBI entrez gene - 431611     See in Manteia.
RefSeq - XM_429163
swissprot - F1NU41
Ensembl - ENSGALG00000015176
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gna14aENSDARG00000025013Danio rerio
 GNA14ENSG00000156049Homo sapiens
 Gna14ENSMUSG00000024697Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GNA11ENSGALG0000000323879
GNAQ / G protein subunit alpha q / P21279* / P50148* / guanine nucleotide binding protein, alpha q polypeptide*ENSGALG0000001517778
GNAI1 / guanine nucleotide-binding protein G(i) subunit alpha-1 / P63096* / B2RSH2* / G protein subunit alpha i1* / guanine nucleotide binding protein (G protein), alpha inhibiting 1*ENSGALG0000000838251
GNAI3 / guanine nucleotide-binding protein G(k) subunit alpha / P08754* / Q9DC51* / G protein subunit alpha i3* / guanine nucleotide binding protein (G protein), alpha inhibiting 3*ENSGALG0000004170051
GNAO1 / G protein subunit alpha o1 / P09471* / P18872* / guanine nucleotide binding protein, alpha O*ENSGALG0000000316350
GNAI2 / G protein subunit alpha i2 / P04899* / P08752* / guanine nucleotide binding protein (G protein), alpha inhibiting 2*ENSGALG0000003564550
GNAT3 / G protein subunit alpha transducin 3 / A8MTJ3* / Q3V3I2* / guanine nucleotide binding protein, alpha transducing 3*ENSGALG0000000842749
GNAT1 / G protein subunit alpha transducin 1 / P11488* / P20612* / guanine nucleotide binding protein, alpha transducing 1*ENSGALG0000002869749
GNAT2 / G protein subunit alpha transducin 2 / P19087* / P50149* / guanine nucleotide binding protein, alpha transducing 2*ENSGALG0000003808449
GNAZ / G protein subunit alpha z / O70443* / P19086* / guanine nucleotide binding protein, alpha z subunit*ENSGALG0000000671948
GNA13 / G protein subunit alpha 13 / P27601* / Q14344* / guanine nucleotide binding protein, alpha 13*ENSGALG0000003602847
GNA12 / G protein subunit alpha 12 / P27600* / Q03113* / guanine nucleotide binding protein, alpha 12*ENSGALG0000000436828


Protein motifs (from Interpro)
Interpro ID Name
 IPR000654  G-protein alpha subunit, group Q
 IPR001019  Guanine nucleotide binding protein (G-protein), alpha subunit
 IPR011025  G protein alpha subunit, helical insertion
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0060158 phospholipase C-activating dopamine receptor signaling pathway IBA
 cellular_componentGO:0005834 heterotrimeric G-protein complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0001664 G-protein coupled receptor binding IBA
 molecular_functionGO:0003924 GTPase activity IBA
 molecular_functionGO:0004871 obsolete signal transducer activity IBA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0019001 guanyl nucleotide binding IEA
 molecular_functionGO:0031683 G-protein beta/gamma-subunit complex binding IBA


Pathways (from Reactome)
Pathway description
G alpha (q) signalling events
ADP signalling through P2Y purinoceptor 1
Thromboxane signalling through TP receptor
Thrombin signalling through proteinase activated receptors (PARs)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008875 PLCB1 / phospholipase C beta 1 / Q9NQ66* / Q9Z1B3* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 *  / reaction / complex
 ENSGALG00000001334 GNB1 / G protein subunit beta 1 / P62873* / P62874* / guanine nucleotide binding protein (G protein), beta 1*  / complex / reaction
 ENSGALG00000008934 PIK3CA / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha / P42336* / P42337* / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform *  / complex / reaction
 ENSGALG00000010357 P2RY1 / P34996 / P2Y purinoceptor 1 / P47900* / P49650* / purinergic receptor P2Y1* / purinergic receptor P2Y, G-protein coupled 1*  / complex
 ENSGALG00000014786 PIK3R1 / phosphoinositide-3-kinase regulatory subunit 1 / P26450* / P27986*  / complex / reaction
 ENSGALG00000027629 GNG2 / G protein subunit gamma 2 / P59768* / P63213* / guanine nucleotide binding protein (G protein), gamma 2*  / complex / reaction
 ENSGALG00000008907 PLCB4 / phospholipase C beta 4 / Q15147*  / complex / reaction
 ENSGALG00000042105 PLCB2 / phospholipase C beta 2 / A3KGF7* / Q00722* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 *  / complex / reaction
 ENSGALG00000023379 F2RL2 / coagulation factor II thrombin receptor like 2 / O00254* / O08675* / Proteinase-activated receptor 3 *  / complex / reaction
 ENSGALG00000031495 TRIO / trio Rho guanine nucleotide exchange factor / O75962* / Q0KL02* / Triple functional domain protein *  / complex / reaction






 

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