ENSGALG00000015304


Gallus gallus
regulationendosomeSNX3membraneproteinearlyvesiclebindingwnttransportphoxhomologousdomainendocytosisresponsebacteriuminvaginationorganizationdockingsignalingpathwaycatabolicprocessviralentryhostcellphagocytosisintralumenalformationlate

Features
Gene ID: ENSGALG00000015304
  
Biological name :SNX3
  
Synonyms : SNX3 / sorting nexin 3
  
Possible biological names infered from orthology : O60493
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 67626201
Gene end: 67645396
  
Corresponding Affymetrix probe sets: Gga.15744.1.S1_at (Chicken Array)   GgaAffx.12984.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000054292
Ensembl peptide - ENSGALP00000024654
NCBI entrez gene - 421772     See in Manteia.
RefSeq - NM_001006408
RefSeq Peptide - NP_001006408
swissprot - Q5ZIA3
swissprot - A0A1D5PN53
Ensembl - ENSGALG00000015304
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 snx3ENSDARG00000008678Danio rerio
 SNX3ENSG00000112335Homo sapiens
 Snx3ENSMUSG00000019804Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SNX12 / sorting nexin-12 / Q9UMY4*ENSGALG0000000565981
SNX11 / sorting nexin 11 / Q91WL6* / Q9Y5W9*ENSGALG0000001755328
SNX10 / sorting nexin-10 / Q9CWT3* / Q9Y5X0*ENSGALG0000001104623


Protein motifs (from Interpro)
Interpro ID Name
 IPR001683  Phox homologous domain


Gene Ontology (GO)
establishment of localizationresponse to external stimulusresponse to biotic stimuluscellular component organizationmembrane dockingcell communicationcellular response to stimulusnitrogen compound metabolic processcatabolic processprimary metabolic processorganic substance metabolic processinterspecies interaction between organismsmacromolecule localizationcellular localizationestablishment of localizationresponse to external stimulusresponse to biotic stimuluscellular component organizationmembrane dockingcell communicationcellular response to stimulusnitrogen compound metabolic processcatabolic processprimary metabolic processorganic substance metabolic processinterspecies interaction between organismsmacromolecule localizationcellular localizationestablishment of localizationresponse to external stimulusresponse to biotic stimuluscellular component organizationmembrane dockingcell communicationcellular response to stimulusnitrogen compound metabolic processcatabolic processprimary metabolic processorganic substance metabolic processinterspecies interaction between organismsmacromolecule localizationcellular localizationestablishment of localizationresponse to external stimulusresponse to biotic stimuluscellular component organizationmembrane dockingcell communicationcellular response to stimulusnitrogen compound metabolic processcatabolic processprimary metabolic processorganic substance metabolic processinterspecies interaction between organismsmacromolecule localizationcellular localizationestablishment of localizationresponse to external stimulusresponse to biotic stimuluscellular component organizationmembrane dockingcell communicationcellular response to stimulusnitrogen compound metabolic processcatabolic processprimary metabolic processorganic substance metabolic processinterspecies interaction between organismsmacromolecule localizationcellular localizationestablishment of localizationresponse to external stimulusresponse to biotic stimuluscellular component organizationmembrane dockingcell communicationcellular response to stimulusnitrogen compound metabolic processcatabolic processprimary metabolic processorganic substance metabolic processinterspecies interaction between organismsmacromolecule localizationcellular localizationestablishment of localizationresponse to external stimulusresponse to biotic stimuluscellular component organizationmembrane dockingcell communicationcellular response to stimulusnitrogen compound metabolic processcatabolic processprimary metabolic processorganic substance metabolic processinterspecies interaction between organismsmacromolecule localizationcellular localizationestablishment of localizationresponse to external stimulusresponse to biotic stimuluscellular component organizationmembrane dockingcell communicationcellular response to stimulusnitrogen compound metabolic processcatabolic processprimary metabolic processorganic substance metabolic processinterspecies interaction between organismsmacromolecule localizationcellular localizationestablishment of localizationresponse to external stimulusresponse to biotic stimuluscellular component organizationmembrane dockingcell communicationcellular response to stimulusnitrogen compound metabolic processcatabolic processprimary metabolic processorganic substance metabolic processinterspecies interaction between organismsmacromolecule localizationcellular localizationestablishment of localizationresponse to external stimulusresponse to biotic stimuluscellular component organizationmembrane dockingcell communicationcellular response to stimulusnitrogen compound metabolic processcatabolic processprimary metabolic processorganic substance metabolic processinterspecies interaction between organismsmacromolecule localizationcellular localizationestablishmestablishment of localizationresponse tresponse to external stimulusresponse tresponse to biotic stimuluscellular ccellular component organizationmembrane dmembrane dockingcell commucell communicationcellular rcellular response to stimulusnitrogen cnitrogen compound metabolic processcatabolic catabolic processprimary meprimary metabolic processorganic suorganic substance metabolic processinterspeciinterspecies interaction between organismsmacromolecmacromolecule localizationcellular lcellular localization
protein bindinglipid bindingion bindingprotein bindinglipid bindingion bindingprotein bindinglipid bindingion bindingprotein bindinglipid bindingion bindingprotein bindinglipid bindingion bindingprotein bindinglipid bindingion bindingprotein bindinglipid bindingion bindingprotein bindinglipid bindingion bindingprotein bindinglipid bindingion bindingprotein bindinglipid bindingion bindingprotein bindingprotein bindinglipid bindinglipid bindingion bindingion binding
cellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellcellorganelleorganellemembranemembraneprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IBA
 biological_processGO:0009617 response to bacterium IEA
 biological_processGO:0010324 membrane invagination IEA
 biological_processGO:0016050 vesicle organization IBA
 biological_processGO:0022615 protein to membrane docking IEA
 biological_processGO:0030111 regulation of Wnt signaling pathway IEA
 biological_processGO:0042177 negative regulation of protein catabolic process IEA
 biological_processGO:0046597 negative regulation of viral entry into host cell IEA
 biological_processGO:0050765 negative regulation of phagocytosis IEA
 biological_processGO:0051224 negative regulation of protein transport IEA
 biological_processGO:0070676 intralumenal vesicle formation IEA
 biological_processGO:2000642 negative regulation of early endosome to late endosome transport IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IBA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0019898 extrinsic component of membrane IBA
 cellular_componentGO:0030136 clathrin-coated vesicle IEA
 cellular_componentGO:0030904 retromer complex IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0032009 early phagosome IEA
 molecular_functionGO:0019903 protein phosphatase binding IEA
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004174 VPS26A / VPS26, retromer complex component A / O75436* / P40336*  / complex / reaction
 ENSGALG00000005951 VPS29L / VPS29* / Q9QZ88* / Q9UBQ0* / VPS29, retromer complex component*  / complex / reaction
 ENSGALG00000004529 VPS29 / Q5ZIL2 / Vacuolar protein sorting-associated protein 29 / Q9UBQ0* / Q9QZ88* / VPS29, retromer complex component*  / complex / reaction






 

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