ENSGALG00000015529


Gallus gallus

Features
Gene ID: ENSGALG00000015529
  
Biological name :WFS1
  
Synonyms : WFS1 / wolframin ER transmembrane glycoprotein
  
Possible biological names infered from orthology : O76024 / P56695
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 80079135
Gene end: 80109860
  
Corresponding Affymetrix probe sets: Gga.11257.1.S1_s_at (Chicken Array)   GgaAffx.9890.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000024991
NCBI entrez gene - 422857     See in Manteia.
RefSeq - XM_015285822
RefSeq - XM_420803
swissprot - F1NQG0
Ensembl - ENSGALG00000015529
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wfs1aENSDARG00000062341Danio rerio
 wfs1bENSDARG00000074617Danio rerio
 WFS1ENSG00000109501Homo sapiens
 Wfs1ENSMUSG00000039474Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026208  Wolframin
 IPR026209  Wolframin family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0003091 renal water homeostasis IEA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0007605 sensory perception of sound IEA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IEA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IEA
 biological_processGO:0031398 positive regulation of protein ubiquitination IEA
 biological_processGO:0032469 endoplasmic reticulum calcium ion homeostasis IEA
 biological_processGO:0034976 response to endoplasmic reticulum stress IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0043069 negative regulation of programmed cell death IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0045927 positive regulation of growth IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0050877 nervous system process IEA
 biological_processGO:0051247 positive regulation of protein metabolic process IEA
 biological_processGO:0051928 positive regulation of calcium ion transport IEA
 biological_processGO:0055074 calcium ion homeostasis IEA
 biological_processGO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IEA
 biological_processGO:1903892 negative regulation of ATF6-mediated unfolded protein response IEA
 biological_processGO:2000675 negative regulation of type B pancreatic cell apoptotic process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0051117 ATPase binding IEA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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