ENSGALG00000016124


Gallus gallus

Features
Gene ID: ENSGALG00000016124
  
Biological name :HADH
  
Synonyms : HADH / hydroxyacyl-CoA dehydrogenase
  
Possible biological names infered from orthology : Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial / Q16836 / Q61425
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 38219463
Gene end: 38236405
  
Corresponding Affymetrix probe sets: Gga.4749.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000025929
Ensembl peptide - ENSGALP00000061622
NCBI entrez gene - 420290     See in Manteia.
RefSeq - NM_001277897
RefSeq Peptide - NP_001264826
swissprot - E1BZH9
swissprot - A0A1L1RS37
Ensembl - ENSGALG00000016124
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hadhENSDARG00000030765Danio rerio
 HADHENSG00000138796Homo sapiens
 HadhENSMUSG00000027984Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EHHADH / enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase / Q08426* / Q9DBM2* / Peroxisomal bifunctional enzyme Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase 3-hydroxyacyl-CoA de...ENSGALG0000000668030
HADHA / hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha / P40939* / Q8BMS1* / hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzym...ENSGALG0000001653630


Protein motifs (from Interpro)
Interpro ID Name
 IPR006108  3-hydroxyacyl-CoA dehydrogenase, C-terminal
 IPR006176  3-hydroxyacyl-CoA dehydrogenase, NAD binding
 IPR006180  3-hydroxyacyl-CoA dehydrogenase, conserved site
 IPR008927  6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
 IPR013328  6-phosphogluconate dehydrogenase, domain 2
 IPR016040  NAD(P)-binding domain
 IPR022694  3-hydroxyacyl-CoA dehydrogenase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 molecular_functionGO:0003857 3-hydroxyacyl-CoA dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0070403 NAD+ binding IEA


Pathways (from Reactome)
Pathway description
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
Beta oxidation of octanoyl-CoA to hexanoyl-CoA
Beta oxidation of hexanoyl-CoA to butanoyl-CoA
Beta oxidation of butanoyl-CoA to acetyl-CoA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000016124 HADH / hydroxyacyl-CoA dehydrogenase / Q16836* / Q61425* / Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial *  / complex






 

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