ENSGALG00000016431


Gallus gallus

Features
Gene ID: ENSGALG00000016431
  
Biological name :PAX5
  
Synonyms : paired box 5 / PAX5
  
Possible biological names infered from orthology : Paired box protein Pax-5 / Q02548 / Q02650
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 81789479
Gene end: 81896738
  
Corresponding Affymetrix probe sets: Gga.400.1.S1_at (Chicken Array)   GgaAffx.10517.1.S1_at (Chicken Array)   GgaAffx.24958.1.S1_at (Chicken Array)   GgaAffx.24958.2.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000052485
Ensembl peptide - ENSGALP00000026458
Ensembl peptide - ENSGALP00000044234
NCBI entrez gene - 387330     See in Manteia.
RefSeq - XM_015280784
RefSeq - NM_204424
RefSeq Peptide - NP_989755
swissprot - A0A0C6E619
swissprot - Q9W601
swissprot - F1NKV2
Ensembl - ENSGALG00000016431
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pax5ENSDARG00000037383Danio rerio
 PAX5ENSG00000196092Homo sapiens
 Pax5ENSMUSG00000014030Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PAX2 / paired box 2 / Q02962*ENSGALG0000000568971
PAX7 / paired box 7 / P23759* / P47239* / Paired box protein Pax-7 *ENSGALG0000004320440
PAX6 / paired box 6 / P26367* / P63015* / Paired box protein Pax-6 *ENSGALG0000001212338
PAX1 / paired box 1 / P09084* / P15863* / Paired box protein Pax-1 *ENSGALG0000003904034
PAX9 / paired box protein Pax-9 / P47242* / P55771* / paired box 9*ENSGALG0000001011431
PAX3 / paired box protein Pax-3 / P23760* / P24610* / paired box 3*ENSGALG0000003094419


Protein motifs (from Interpro)
Interpro ID Name
 IPR001523  Paired domain
 IPR009057  Homeobox-like domain superfamily
 IPR011991  ArsR-like helix-turn-helix domain
 IPR022130  Paired-box protein 2 C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007568 aging IEA
 biological_processGO:0021670 lateral ventricle development IEA
 biological_processGO:0021987 cerebral cortex development IEA
 biological_processGO:0030534 adult behavior IEA
 biological_processGO:0035914 skeletal muscle cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IEA
 biological_processGO:0051573 negative regulation of histone H3-K9 methylation IEA
 cellular_componentGO:0001650 fibrillar center IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
RUNX1 regulates transcription of genes involved in BCR signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000016022 RUNX1 / runt related transcription factor 1 / Q01196*  / complex / reaction






 

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