ENSGALG00000016708


Gallus gallus
alphabis-adenosyl-triphosphataseprocessmembraneactivityENPP4typephosphodiesterasenucleotidepyrophosphatasephosphatetransferasealkalinephosphatase-likebetacoredomainsuperfamilyenppmetabolicregulationbloodcoagulationpurineribonucleosidecatabolicintegral

Features
Gene ID: ENSGALG00000016708
  
Biological name :ENPP4
  
Synonyms : ectonucleotide pyrophosphatase/phosphodiesterase 4 / ENPP4
  
Possible biological names infered from orthology : Mus musculus ectonucleotide pyrophosphatase/phosphodiesterase 4 (Enpp4), transcript variant 2, mRNA. / Q8BTJ4 / Q9Y6X5
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 110170121
Gene end: 110176738
  
Corresponding Affymetrix probe sets: GgaAffx.10691.2.S1_s_at (Chicken Array)   GgaAffx.12263.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000035900
Ensembl peptide - ENSGALP00000062564
Ensembl peptide - ENSGALP00000059393
Ensembl peptide - ENSGALP00000059347
Ensembl peptide - ENSGALP00000045392
NCBI entrez gene - 422055     See in Manteia.
RefSeq - NM_001006422
RefSeq - XM_015285142
RefSeq Peptide - NP_001006422
swissprot - A0A1D5NYD5
swissprot - A0A1L1RUR0
swissprot - F1N9T9
swissprot - A0A1L1RKV5
swissprot - A0A1L1RKQ7
Ensembl - ENSGALG00000016708
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 enpp4ENSDARG00000006877Danio rerio
 ENPP4ENSG00000001561Homo sapiens
 Enpp4ENSMUSG00000023961Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENPP3 / ectonucleotide pyrophosphatase/phosphodiesterase 3 / O14638* / Q6DYE8* / Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 Alkaline phosphodiesterase I Nucleotide pyr...ENSGALG0000003758734
ENPP6 / ectonucleotide pyrophosphatase/phosphodiesterase 6 / Q6UWR7* / Q8BGN3* / Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 *ENSGALG0000001064530
ENPP2 / ectonucleotide pyrophosphatase/phosphodiesterase 2 / Q13822* / Q9R1E6* / Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 *ENSGALG0000003274630
ENPP1 / ectonucleotide pyrophosphatase/phosphodiesterase 1 / P22413* / ectonucleotide pyrophosphatase/phosphodiesterase family member 1 isoform 3 *ENSGALG0000003439730
ENPP7 / ectonucleotide pyrophosphatase/phosphodiesterase 7 / Q6UWV6*ENSGALG0000001374323


Protein motifs (from Interpro)
Interpro ID Name
 IPR002591  Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase
 IPR017849  Alkaline phosphatase-like, alpha/beta/alpha
 IPR017850  Alkaline-phosphatase-like, core domain superfamily
 IPR029879  Bis(5"-adenosyl)-triphosphatase ENPP4


Gene Ontology (GO)
response to stressresponse to external stimulusregulation of biological qualitycoagulationnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processresponse to stressresponse to external stimulusregulation of biological qualitycoagulationnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processresponse to stressresponse to external stimulusregulation of biological qualitycoagulationnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processresponse to stressresponse to external stimulusregulation of biological qualitycoagulationnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processresponse to stressresponse to external stimulusregulation of biological qualitycoagulationnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processresponse to stressresponse to external stimulusregulation of biological qualitycoagulationnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processresponse to stressresponse to external stimulusregulation of biological qualitycoagulationnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processresponse to stressresponse to external stimulusregulation of biological qualitycoagulationnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processresponse to stressresponse to external stimulusregulation of biological qualitycoagulationnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processresponse to stressresponse to external stimulusregulation of biological qualitycoagulationnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processresponse to stresponse to stressresponse to exresponse to external stimulusregulation of regulation of biological qualitycoagulationcoagulationnitrogen componitrogen compound metabolic processcatabolic proccatabolic processcellular metabcellular metabolic processprimary metaboprimary metabolic processsmall moleculesmall molecule metabolic processorganic substaorganic substance metabolic process
hydrolase activityhydrolase activityhydrolase activityhydrolase activityhydrolase activityhydrolase activityhydrolase activityhydrolase activityhydrolase activityhydrolase activityhydrolase activityhydrolase activity
membranemembranemembranemembranemembranemembranemembranemembranemembranemembranemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0030194 positive regulation of blood coagulation IEA
 biological_processGO:0046130 purine ribonucleoside catabolic process IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0047710 bis(5"-adenosyl)-triphosphatase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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