ENSG00000001561


Homo sapiens

Features
Gene ID: ENSG00000001561
  
Biological name :ENPP4
  
Synonyms : ectonucleotide pyrophosphatase/phosphodiesterase 4 / ENPP4 / Q9Y6X5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p21.1
Gene start: 46129993
Gene end: 46146699
  
Corresponding Affymetrix probe sets: 204160_s_at (Human Genome U133 Plus 2.0 Array)   204161_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000318066
NCBI entrez gene - 22875     See in Manteia.
OMIM - 617000
RefSeq - NM_014936
RefSeq Peptide - NP_055751
swissprot - Q9Y6X5
Ensembl - ENSG00000001561
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 enpp4ENSDARG00000006877Danio rerio
 ENPP4ENSGALG00000016708Gallus gallus
 Enpp4ENSMUSG00000023961Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENPP5 / Q9UJA9 / ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)ENSG0000011279646
ENPP1 / P22413 / ectonucleotide pyrophosphatase/phosphodiesterase 1ENSG0000019759435
ENPP3 / O14638 / ectonucleotide pyrophosphatase/phosphodiesterase 3ENSG0000015426934
ENPP2 / Q13822 / ectonucleotide pyrophosphatase/phosphodiesterase 2ENSG0000013696031
ENPP6 / Q6UWR7 / ectonucleotide pyrophosphatase/phosphodiesterase 6ENSG0000016430330
ENPP7 / Q6UWV6 / ectonucleotide pyrophosphatase/phosphodiesterase 7ENSG0000018215628


Protein motifs (from Interpro)
Interpro ID Name
 IPR002591  Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase
 IPR017849  Alkaline phosphatase-like, alpha/beta/alpha
 IPR017850  Alkaline-phosphatase-like, core domain superfamily
 IPR029879  Bis(5"-adenosyl)-triphosphatase ENPP4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007596 blood coagulation IEA
 biological_processGO:0007599 hemostasis IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0030194 positive regulation of blood coagulation IDA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0046130 purine ribonucleoside catabolic process IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0101003 ficolin-1-rich granule membrane TAS
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047710 bis(5"-adenosyl)-triphosphatase activity IDA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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