ENSGALG00000016820


Gallus gallus

Features
Gene ID: ENSGALG00000016820
  
Biological name :GAS6
  
Synonyms : GAS6 / growth arrest specific 6
  
Possible biological names infered from orthology : Growth arrest-specific protein 6 / Q14393 / Q61592
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 137167180
Gene end: 137204808
  
Corresponding Affymetrix probe sets: Gga.8078.1.S1_at (Chicken Array)   GgaAffx.10766.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000027103
Ensembl peptide - ENSGALP00000044378
NCBI entrez gene - 418737     See in Manteia.
RefSeq - XM_015277909
swissprot - A0A1D5NVK3
swissprot - F1P3F0
Ensembl - ENSGALG00000016820
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gas6ENSDARG00000007804Danio rerio
 GAS6ENSG00000183087Homo sapiens
 Gas6ENSMUSG00000031451Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PROS1 / protein S / P07225* / Q08761* / protein S (alpha)*ENSGALG0000001540943


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000294  Gamma-carboxyglutamic acid-rich (GLA) domain
 IPR000742  EGF-like domain
 IPR001791  Laminin G domain
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR017857  Coagulation factor-like, Gla domain superfamily
 IPR018097  EGF-like calcium-binding, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0001961 positive regulation of cytokine-mediated signaling pathway IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006909 phagocytosis IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007167 enzyme linked receptor protein signaling pathway IEA
 biological_processGO:0007596 blood coagulation IEA
 biological_processGO:0009267 cellular response to starvation IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway IEA
 biological_processGO:0010934 macrophage cytokine production IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IEA
 biological_processGO:0019064 fusion of virus membrane with host plasma membrane IEA
 biological_processGO:0019079 viral genome replication IEA
 biological_processGO:0031589 cell-substrate adhesion IEA
 biological_processGO:0032689 negative regulation of interferon-gamma production IEA
 biological_processGO:0032715 negative regulation of interleukin-6 production IEA
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IEA
 biological_processGO:0032825 positive regulation of natural killer cell differentiation IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0033159 negative regulation of protein import into nucleus, translocation IEA
 biological_processGO:0035457 cellular response to interferon-alpha IEA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0035754 B cell chemotaxis IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0043277 apoptotic cell clearance IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0043491 protein kinase B signaling IEA
 biological_processGO:0045860 positive regulation of protein kinase activity IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0046718 viral entry into host cell IEA
 biological_processGO:0046813 receptor-mediated virion attachment to host cell IEA
 biological_processGO:0046827 positive regulation of protein export from nucleus IEA
 biological_processGO:0048146 positive regulation of fibroblast proliferation IEA
 biological_processGO:0050711 negative regulation of interleukin-1 secretion IEA
 biological_processGO:0050766 positive regulation of phagocytosis IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IEA
 biological_processGO:0061098 positive regulation of protein tyrosine kinase activity IEA
 biological_processGO:0070168 negative regulation of biomineral tissue development IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:0071307 cellular response to vitamin K IEA
 biological_processGO:0071363 cellular response to growth factor stimulus IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 biological_processGO:0097028 dendritic cell differentiation IEA
 biological_processGO:0097241 hematopoietic stem cell migration to bone marrow IEA
 biological_processGO:1900142 negative regulation of oligodendrocyte apoptotic process IEA
 biological_processGO:1900165 negative regulation of interleukin-6 secretion IEA
 biological_processGO:2000270 negative regulation of fibroblast apoptotic process IEA
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process IEA
 biological_processGO:2000510 positive regulation of dendritic cell chemotaxis IEA
 biological_processGO:2000669 negative regulation of dendritic cell apoptotic process IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0001786 phosphatidylserine binding IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005245 voltage-gated calcium channel activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0030296 protein tyrosine kinase activator activity IEA
 molecular_functionGO:0030971 receptor tyrosine kinase binding IEA
 molecular_functionGO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process IEA
 molecular_functionGO:0048018 receptor ligand activity IEA
 molecular_functionGO:0060090 molecular adaptor activity IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
Removal of aminoterminal propeptides from gamma-carboxylated proteins
Cell surface interactions at the vascular wall
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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