ENSGALG00000016832


Gallus gallus

Features
Gene ID: ENSGALG00000016832
  
Biological name :PROZ
  
Synonyms : protein Z, vitamin K dependent plasma glycoprotein / PROZ
  
Possible biological names infered from orthology : P22891 / Q9CQW3
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 137560703
Gene end: 137567368
  
Corresponding Affymetrix probe sets: GgaAffx.10775.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000027123
NCBI entrez gene - 418746     See in Manteia.
RefSeq - XM_416945
swissprot - E1BT71
Ensembl - ENSGALG00000016832
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prozaENSDARG00000037783Danio rerio
 prozbENSDARG00000076900Danio rerio
 PROZENSG00000126231Homo sapiens
 ProzENSMUSG00000031445Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
F10 / P25155 / Coagulation factor X Factor X light chain Factor X heavy chain Activated factor Xa heavy chain / O88947* / P00742* / coagulation factor X*ENSGALG0000002667736
F7 / coagulation factor VII precursor / P08709* / P70375* / coagulation factor VII* / Coagulation factor VII Factor VII light chain Factor VII heavy chain*ENSGALG0000001683335
PROC / vitamin K-dependent protein C precursor / P33587* / P04070* / protein C, inactivator of coagulation factors Va and VIIIa* / Vitamin K-dependent protein C Vitamin K-dependent protein...ENSGALG0000000178034
F9 / coagulation factor IX precursor / P00740* / P16294* / coagulation factor IX* / Coagulation factor IX Coagulation factor IXa light chain Coagulation factor IXa heavy chain*ENSGALG0000000651333
ENSGALG0000004562229
MASP2 / mannan-binding lectin serine protease 2 precursor / O00187* / Q91WP0* / mannan binding lectin serine peptidase 2* / Mannan-binding lectin serine protease 2 Mannan-binding lectin se...ENSGALG0000000301623
C1R* / C1ra* / C1rb* / C1RL* / Q9NZP8* / P00736* / Q3UZ09* / Q8CFG9* / Q8CG16* / complement C1r* / complement C1r subcomponent like* / Complement C1r subcomponent-like protein * / Complemen...ENSGALG0000001465922
MASP1 / mannan-binding lectin serine protease 1 precursor / P48740* / P98064* / mannan binding lectin serine peptidase 1* / Mus musculus mannan-binding lectin serine peptidase 1 (Masp1), t...ENSGALG0000000741921
PAMR1 / peptidase domain containing associated with muscle regeneration 1 / Q6UXH9* / Q8BU25* / Inactive serine protease PAMR1 *ENSGALG0000000788621
C1S / complement C1s subcomponent precursor / C1s1* / C1s2* / Q8CFG8* / P09871* / complement C1s* / complement component 1, s subcomponent 1* / complement component 1, s subcomponent 2*ENSGALG0000001460320


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000294  Gamma-carboxyglutamic acid-rich (GLA) domain
 IPR000742  EGF-like domain
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR001881  EGF-like calcium-binding domain
 IPR009003  Peptidase S1, PA clan
 IPR012224  Peptidase S1A, coagulation factor VII/IX/X/C/Z
 IPR013032  EGF-like, conserved site
 IPR017857  Coagulation factor-like, Gla domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007596 blood coagulation IEA
 biological_processGO:0030195 negative regulation of blood coagulation IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0004252 serine-type endopeptidase activity IBA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
Removal of aminoterminal propeptides from gamma-carboxylated proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008341 FURIN / furin, paired basic amino acid cleaving enzyme / P09958* / P23188*  / reaction






 

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