ENSGALG00000014603


Gallus gallus

Features
Gene ID: ENSGALG00000014603
  
Biological name :C1S
  
Synonyms : C1S / complement C1s subcomponent precursor
  
Possible biological names infered from orthology : C1s1 / C1s2 / complement C1s / complement component 1, s subcomponent 1 / complement component 1, s subcomponent 2 / P09871 / Q8CFG8
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 77379603
Gene end: 77388708
  
Corresponding Affymetrix probe sets: GgaAffx.9256.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000023499
NCBI entrez gene - 418294     See in Manteia.
RefSeq - NM_001030777
RefSeq Peptide - NP_001025948
swissprot - F1N803
Ensembl - ENSGALG00000014603
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 c1rENSDARG00000100248Danio rerio
 wu:fd46c06ENSDARG00000102094Danio rerio
 C1SENSG00000182326Homo sapiens
 C1s1ENSMUSG00000038521Mus musculus
 C1s2ENSMUSG00000079343Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MASP1 / mannan-binding lectin serine protease 1 precursor / P48740* / P98064* / mannan binding lectin serine peptidase 1* / Mus musculus mannan-binding lectin serine peptidase 1 (Masp1), t...ENSGALG0000000741937
C1R* / C1ra* / C1rb* / C1RL* / Q9NZP8* / P00736* / Q3UZ09* / Q8CFG9* / Q8CG16* / complement C1r* / complement C1r subcomponent like* / Complement C1r subcomponent-like protein * / Complemen...ENSGALG0000001465936
MASP2 / mannan-binding lectin serine protease 2 precursor / O00187* / Q91WP0* / mannan binding lectin serine peptidase 2* / Mannan-binding lectin serine protease 2 Mannan-binding lectin se...ENSGALG0000000301635
PAMR1 / peptidase domain containing associated with muscle regeneration 1 / Q6UXH9* / Q8BU25* / Inactive serine protease PAMR1 *ENSGALG0000000788618
PROC / vitamin K-dependent protein C precursor / P33587* / P04070* / protein C, inactivator of coagulation factors Va and VIIIa* / Vitamin K-dependent protein C Vitamin K-dependent protein...ENSGALG0000000178017
F9 / coagulation factor IX precursor / P00740* / P16294* / coagulation factor IX* / Coagulation factor IX Coagulation factor IXa light chain Coagulation factor IXa heavy chain*ENSGALG0000000651317
F7 / coagulation factor VII precursor / P08709* / P70375* / coagulation factor VII* / Coagulation factor VII Factor VII light chain Factor VII heavy chain*ENSGALG0000001683317
ENSGALG0000004562217
F10 / P25155 / Coagulation factor X Factor X light chain Factor X heavy chain Activated factor Xa heavy chain / O88947* / P00742* / coagulation factor X*ENSGALG0000002667716
PROZ / protein Z, vitamin K dependent plasma glycoprotein / P22891* / Q9CQW3*ENSGALG0000001683212


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000436  Sushi/SCR/CCP domain
 IPR000859  CUB domain
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR001881  EGF-like calcium-binding domain
 IPR009003  Peptidase S1, PA clan
 IPR018097  EGF-like calcium-binding, conserved site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001867 complement activation, lectin pathway IBA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006958 complement activation, classical pathway IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0004252 serine-type endopeptidase activity IBA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Initial triggering of complement
Classical antibody-mediated complement activation
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr