ENSDARG00000102094


Danio rerio

Features
Gene ID: ENSDARG00000102094
  
Biological name :wu:fd46c06
  
Synonyms : wu:fd46c06
  
Possible biological names infered from orthology : C1S / C1s1 / C1s2 / complement C1s / complement component 1, s subcomponent 1 / complement component 1, s subcomponent 2 / P09871 / Q8CFG8
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 31658196
Gene end: 31661536
  
Corresponding Affymetrix probe sets: Dr.22244.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000135637
NCBI entrez gene - 793504     See in Manteia.
RefSeq - NM_001114449
RefSeq Peptide - NP_001107921
swissprot - A0A0R4IIJ1
ZFIN ID - ZDB-GENE-030131-4645
Ensembl - ENSDARG00000102094
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 C1SENSGALG00000014603Gallus gallus
 C1SENSG00000182326Homo sapiens
 C1s1ENSMUSG00000038521Mus musculus
 C1s2ENSMUSG00000079343Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
c1r / complement component 1, r subcomponent / C1S* / P09871* / complement C1s*ENSDARG0000010024869
masp2 / mannan-binding lectin serine peptidase 2 / O00187* / Q91WP0* / Mannan-binding lectin serine protease 2 Mannan-binding lectin serine protease 2 A chain Mannan-binding lectin serine p...ENSDARG0000000798831
masp1 / mannan-binding lectin serine peptidase 1 / P48740* / P98064* / Mus musculus mannan-binding lectin serine peptidase 1 (Masp1), transcript variant 1, mRNA.*ENSDARG0000006872631
CABZ01044048.1ENSDARG0000001146321
f9a / coagulation factor IXa / F9* / P16294* / P00740* / coagulation factor IX* / Coagulation factor IX Coagulation factor IXa light chain Coagulation factor IXa heavy chain*ENSDARG0000001009720
f10 / coagulation factor X / O88947* / P00742* / Coagulation factor X Factor X light chain Factor X heavy chain Activated factor Xa heavy chain*ENSDARG0000008858120
f9b / coagulation factor IXb / F9* / P16294* / P00740* / coagulation factor IX* / Coagulation factor IX Coagulation factor IXa light chain Coagulation factor IXa heavy chain*ENSDARG0000002949319
f7 / coagulation factor VII / P08709* / P70375* / Coagulation factor VII Factor VII light chain Factor VII heavy chain*ENSDARG0000003486219
pamr1 / peptidase domain containing associated with muscle regeneration 1 / Q6UXH9* / Q8BU25* / Inactive serine protease PAMR1 *ENSDARG0000009348019
zgc:163025 / F7 (1 of many) / F7* / P08709* / P70375* / coagulation factor VII* / Coagulation factor VII Factor VII light chain Factor VII heavy chain*ENSDARG0000010078219
si:ch211-102l7.3 / PAMR1 (1 of many) / PAMR1* / Q6UXH9* / Q8BU25* / Inactive serine protease PAMR1 * / peptidase domain containing associated with muscle regeneration 1*ENSDARG0000010318419
proca / protein C (inactivator of coagulation factors Va and VIIIa), a / PROC* / P33587* / P04070* / protein C, inactivator of coagulation factors Va and VIIIa* / Vitamin K-dependent protei...ENSDARG0000003825818
proca / protein C (inactivator of coagulation factors Va and VIIIa), a / PROC* / P33587* / P04070* / protein C, inactivator of coagulation factors Va and VIIIa* / Vitamin K-dependent protei...ENSDARG0000009307918
f7i / coagulation factor VIIi / F7* / P70375* / P08709* / coagulation factor VII* / Coagulation factor VII Factor VII light chain Factor VII heavy chain*ENSDARG0000007582717
hp / haptoglobin / HPR* / P00738* / P00739* / Q61646* / haptoglobin-related protein* / Haptoglobin Haptoglobin alpha chain Haptoglobin beta chain*ENSDARG0000005189014
proza / protein Z, vitamin K-dependent plasma glycoprotein a / PROZ* / P22891* / protein Z, vitamin K dependent plasma glycoprotein*ENSDARG0000003778313
c1s / complement component 1, s subcomponentENSDARG0000010059912
prozb / protein Z, vitamin K-dependent plasma glycoprotein b / PROZ* / P22891* / Q9CQW3* / protein Z, vitamin K dependent plasma glycoprotein*ENSDARG0000007690011


Protein motifs (from Interpro)
Interpro ID Name
 IPR000436  Sushi/SCR/CCP domain
 IPR000859  CUB domain
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA


Pathways (from Reactome)
Pathway description
Initial triggering of complement
Classical antibody-mediated complement activation
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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