ENSGALG00000016834


Gallus gallus

Features
Gene ID: ENSGALG00000016834
  
Biological name :MCF2L
  
Synonyms : MCF.2 cell line derived transforming sequence like / MCF2L
  
Possible biological names infered from orthology : O15068
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 137606558
Gene end: 137750320
  
Corresponding Affymetrix probe sets: Gga.12805.1.S1_s_at (Chicken Array)   Gga.17736.1.S1_at (Chicken Array)   GgaAffx.10777.1.S1_at (Chicken Array)   GgaAffx.10777.1.S1_s_at (Chicken Array)   GgaAffx.10777.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000042945
Ensembl peptide - ENSGALP00000027129
NCBI entrez gene - 418748     See in Manteia.
RefSeq - XM_015277854
RefSeq - NM_001252063
RefSeq - XM_015277850
RefSeq - XM_015277852
RefSeq - XM_015277853
RefSeq - XM_015277842
RefSeq - XM_015277843
RefSeq - XM_015277844
RefSeq - XM_015277845
RefSeq - XM_015277846
RefSeq - XM_015277847
RefSeq - XM_015277848
RefSeq - XM_015277849
RefSeq Peptide - NP_001238992
swissprot - R4GL74
swissprot - E1BT68
Ensembl - ENSGALG00000016834
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mcf2laENSDARG00000075859Danio rerio
 mcf2lbENSDARG00000076480Danio rerio
 MCF2LENSG00000126217Homo sapiens
 Mcf2lENSMUSG00000031442Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MCF2L2 / MCF.2 cell line derived transforming sequence-like 2 / Q86YR7*ENSGALG0000000874452
MCF2 / MCF.2 cell line derived transforming sequence / P10911*ENSGALG0000000656242
KALRN / kalirin RhoGEF kinase / A2CG49* / O60229* / Kalirin *ENSGALG0000001174425
TRIO / trio Rho guanine nucleotide exchange factor / O75962* / Q0KL02* / Triple functional domain protein *ENSGALG0000003149525
A1L390* / Q4VAC9* / PLEKHG3* / pleckstrin homology and RhoGEF domain containing G3* / Pleckstrin homology domain-containing family G member 3 *ENSGALG000000361998
PLEKHG1 / pleckstrin homology and RhoGEF domain containing G1 / Q9ULL1*ENSGALG000000123957
A1L390* / Q4VAC9* / PLEKHG3* / pleckstrin homology and RhoGEF domain containing G3* / Pleckstrin homology domain-containing family G member 3 *ENSGALG000000374097


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001251  CRAL-TRIO lipid binding domain
 IPR001331  Guanine-nucleotide dissociation stimulator, CDC24, conserved site
 IPR001452  SH3 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR018159  Spectrin/alpha-actinin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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