ENSGALG00000017070


Gallus gallus
sisterPDS5Bchromatidcohesionregulationcellproliferationchromatinarmadillo-likehelicalarmadillo-typefoldmitoticnucleoplasmdnabindingseparationchromatidsestablishmentcohesinloadingontoresolution

Features
Gene ID: ENSGALG00000017070
  
Biological name :PDS5B
  
Synonyms : PDS5B / PDS5 cohesin associated factor B
  
Possible biological names infered from orthology : Mus musculus PDS5 cohesin associated factor B (Pds5b), transcript variant 2, mRNA. / Q4VA53 / Q9NTI5
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 174394078
Gene end: 174492314
  
Corresponding Affymetrix probe sets: Gga.15747.1.S1_at (Chicken Array)   Gga.15747.2.S1_s_at (Chicken Array)   GgaAffx.20937.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051214
Ensembl peptide - ENSGALP00000027519
NCBI entrez gene - 418910     See in Manteia.
RefSeq - XM_015277870
RefSeq - XM_015277851
RefSeq - XM_015277859
RefSeq - XM_015277867
RefSeq - NM_001012827
RefSeq - XM_015277841
RefSeq Peptide - NP_001012845
swissprot - F1P3B8
swissprot - A0A1D5PEL0
Ensembl - ENSGALG00000017070
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pds5bENSDARG00000098897Danio rerio
 PDS5BENSG00000083642Homo sapiens
 Pds5bENSMUSG00000034021Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDS5A / sister chromatid cohesion protein PDS5 homolog A / Q29RF7* / PDS5 cohesin associated factor A*ENSGALG0000001428664


Protein motifs (from Interpro)
Interpro ID Name
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
cellular component organizationcell cyclechromosome segregationcellular component organizationcell cyclechromosome segregationcellular component organizationcell cyclechromosome segregationcellular component organizationcell cyclechromosome segregationcellular component organizationcell cyclechromosome segregationcellular component organizationcell cyclechromosome segregationcellular component organizationcell cyclechromosome segregationcellular component organizationcell cyclechromosome segregationcellular component organizationcell cyclechromosome segregationcellular component organizationcell cyclechromosome segregationcellular component organizationcellular component organizationcell cyclecell cyclechromosome segregationchromosome segregation
organic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingorganic cyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingheterocyclic compound binding
cellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0007064 mitotic sister chromatid cohesion IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 cellular_componentGO:0000785 chromatin IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
Separation of Sister Chromatids
Establishment of Sister Chromatid Cohesion
Cohesin Loading onto Chromatin
Resolution of Sister Chromatid Cohesion


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001907 WAPL / wings apart-like protein homolog / Q65Z40* / Q7Z5K2* / WAPL cohesin release factor*  / complex / reaction
 ENSGALG00000003085 CDK1 / cyclin-dependent kinase 1 / P06493* / P11440*  / reaction
 ENSGALG00000004161 CCNB2 / P29332 / G2/mitotic-specific cyclin-B2 / O95067* / P30276* / cyclin B2*  / reaction
 ENSGALG00000006110 PLK1 / serine/threonine-protein kinase PLK1 / P53350* / Q07832* / polo like kinase 1*  / reaction
 ENSGALG00000017070 PDS5B / PDS5 cohesin associated factor B / Q4VA53* / Q9NTI5* / Mus musculus PDS5 cohesin associated factor B (Pds5b), transcript variant 2, mRNA.*  / reaction






 

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