ENSGALG00000017153


Gallus gallus

Features
Gene ID: ENSGALG00000017153
  
Biological name :RDX
  
Synonyms : radixin / RDX
  
Possible biological names infered from orthology : P26043 / P35241
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 179631235
Gene end: 179664820
  
Corresponding Affymetrix probe sets: Gga.13442.1.S1_at (Chicken Array)   Gga.13442.1.S2_s_at (Chicken Array)   GgaAffx.21579.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000021028
NCBI entrez gene - 395511     See in Manteia.
RefSeq - NM_204751
RefSeq - XM_015277633
RefSeq Peptide - NP_990082
swissprot - F1NQD9
Ensembl - ENSGALG00000017153
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RDXENSG00000137710Homo sapiens
 RdxENSMUSG00000032050Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MSN / moesin / P26038* / P26041*ENSGALG0000003961582
EZRENSGALG0000001374277
NF2 / neurofibromin 2 / P35240* / P46662* / Merlin *ENSGALG0000000807347
FARP1 / FERM, ARH/RhoGEF and pleckstrin domain protein 1 / F8VPU2* / Q9Y4F1* / FERM, ARHGEF and pleckstrin domain-containing protein 1 *ENSGALG0000001688627
FARP2 / FERM, ARH/RhoGEF and pleckstrin domain protein 2 / O94887* / Q91VS8* / FERM, ARHGEF and pleckstrin domain-containing protein 2 *ENSGALG0000000578826
FRMD7 / FERM domain containing 7 / A2AD83* / Q6ZUT3* / FERM domain-containing protein 7 *ENSGALG0000002384320
MYLIP / myosin regulatory light chain interacting protein / Q8BM54* / Q8WY64* / E3 ubiquitin-protein ligase MYLIP *ENSGALG0000001270417
ENSGALG0000000236714


Protein motifs (from Interpro)
Interpro ID Name
 IPR000299  FERM domain
 IPR000798  Ezrin/radixin/moesin-like
 IPR008954  Moesin tail domain superfamily
 IPR011174  Ezrin/radixin/moesin
 IPR011259  Ezrin/radixin/moesin, C-terminal
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR018979  FERM, N-terminal
 IPR018980  FERM, C-terminal PH-like domain
 IPR019747  FERM conserved site
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0008361 regulation of cell size IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0030033 microvillus assembly IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0032231 regulation of actin filament bundle assembly IEA
 biological_processGO:0034111 negative regulation of homotypic cell-cell adhesion IEA
 biological_processGO:0034260 negative regulation of GTPase activity IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0045176 apical protein localization IEA
 biological_processGO:0045184 establishment of protein localization IEA
 biological_processGO:0045792 negative regulation of cell size IEA
 biological_processGO:0061028 establishment of endothelial barrier IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 biological_processGO:0097067 cellular response to thyroid hormone stimulus IEA
 biological_processGO:1900027 regulation of ruffle assembly IEA
 biological_processGO:1900087 positive regulation of G1/S transition of mitotic cell cycle IEA
 biological_processGO:1902115 regulation of organelle assembly IEA
 biological_processGO:1902966 positive regulation of protein localization to early endosome IEA
 biological_processGO:1903364 positive regulation of cellular protein catabolic process IEA
 biological_processGO:1903392 negative regulation of adherens junction organization IEA
 biological_processGO:2000643 positive regulation of early endosome to late endosome transport IEA
 cellular_componentGO:0001726 ruffle IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005902 microvillus IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030175 filopodium IEA
 cellular_componentGO:0030864 cortical actin cytoskeleton IEA
 cellular_componentGO:0032420 stereocilium IEA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0045177 apical part of cell IEA
 cellular_componentGO:0071944 cell periphery IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0008092 cytoskeletal protein binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0051117 ATPase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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