ENSGALG00000017485


Gallus gallus

Features
Gene ID: ENSGALG00000017485
  
Biological name :TLR1A
  
Synonyms : TLR1A / toll-like receptor1 precursor
  
Possible biological names infered from orthology : Q15399 / Q9BXR5 / Q9EPQ1 / Q9Y2C9 / TLR1 / TLR10 / TLR6 / toll like receptor 1 / toll like receptor 10 / toll like receptor 6
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 69963233
Gene end: 69968568
  
Corresponding Affymetrix probe sets: GgaAffx.11201.1.S1_s_at (Chicken Array)   GgaAffx.11201.2.A1_at (Chicken Array)   GgaAffx.11201.2.S1_s_at (Chicken Array)   GgaAffx.11201.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000028126
NCBI entrez gene - 426274     See in Manteia.
RefSeq - NM_001007488
RefSeq - XM_015285656
RefSeq - XM_015285657
RefSeq Peptide - NP_001007489
swissprot - F6SU23
Ensembl - ENSGALG00000017485
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tlr1ENSDARG00000100649Danio rerio
 TLR1ENSG00000174125Homo sapiens
 TLR10ENSG00000174123Homo sapiens
 TLR6ENSG00000174130Homo sapiens
 Tlr1ENSMUSG00000044827Mus musculus
 Tlr6ENSMUSG00000051498Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TLR1B / toll-like receptor 6 / TLR1* / TLR6* / TLR10* / Q15399* / Q9Y2C9* / Q9BXR5* / Q9EPQ1* / toll like receptor 1* / toll like receptor 10*ENSGALG0000002709357
TLR2B / toll-like receptor 2 type-2 precursor / TLR2* / O60603* / toll like receptor 2*ENSGALG0000003472228
TLR15 / Gallus gallus toll-like receptor 15 (TLR15), mRNA.ENSGALG0000000816624
TLR21 / Toll-like receptor 21 precursor / Tlr13* / Q6R5N8* / Toll-like receptor 13 *ENSGALG0000003306822
TLR5 / toll-like receptor 5 precursor / O60602* / toll like receptor 5*ENSGALG0000000939220
TLR7 / toll-like receptor 7 / P58681* / Q9NYK1*ENSGALG0000001659020
TLR4 / toll-like receptor 4 precursor / O00206* / Q9QUK6* / toll like receptor 4*ENSGALG0000000700119
TLR3 / toll-like receptor 3 precursor / Q99MB1* / O15455* / toll like receptor 3* / Mus musculus toll-like receptor 3 (Tlr3), transcript variant 3, mRNA.*ENSGALG0000001346817
CD180 / CD180 molecule / Q62192* / Q99467* / CD180 antigen *ENSGALG0000002341113


Protein motifs (from Interpro)
Interpro ID Name
 IPR000157  Toll/interleukin-1 receptor homology (TIR) domain
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR027187  Toll-like receptor 6
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002224 toll-like receptor signaling pathway IBA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002755 MyD88-dependent toll-like receptor signaling pathway IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0032499 detection of peptidoglycan TAS
 biological_processGO:0034166 toll-like receptor 10 signaling pathway IEA
 biological_processGO:0042494 detection of bacterial lipoprotein TAS
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0050707 regulation of cytokine secretion IEA
 biological_processGO:0050729 positive regulation of inflammatory response IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA


Pathways (from Reactome)
Pathway description
Toll Like Receptor 10 (TLR10) Cascade
Regulation of TLR by endogenous ligand


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002496 SFTPA1 / Q8IWL2* / SFTPA2* / Q8IWL1* / surfactant protein A1* / surfactant protein A2* / surfactant associated protein A1*  / complex / reaction
 ENSGALG00000002503 SFTPA2 / Q8IWL2* / SFTPA1* / Q8IWL1* / surfactant protein A1* / surfactant protein A2* / surfactant associated protein A1*  / complex / reaction
 ENSGALG00000017485 TLR1A / toll-like receptor1 precursor / TLR1* / TLR6* / TLR10* / Q15399* / Q9EPQ1* / Q9BXR5* / Q9Y2C9* / toll like receptor 1* / toll like receptor 6* / toll like receptor 10*  / complex
 ENSGALG00000008439 CD36 / platelet glycoprotein 4 / P16671* / Q08857* / CD36 molecule*  / complex / reaction






 

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