ENSGALG00000026207


Gallus gallus

Features
Gene ID: ENSGALG00000026207
  
Biological name :CNTF
  
Synonyms : Ciliary neurotrophic factor / CNTF / Q02011
  
Possible biological names infered from orthology : P26441 / P51642
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 16919059
Gene end: 16920630
  
Corresponding Affymetrix probe sets: Gga.853.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000042605
NCBI entrez gene - 396488     See in Manteia.
RefSeq - NM_205492
RefSeq - XM_015286770
RefSeq Peptide - NP_990823
swissprot - Q02011
Ensembl - ENSGALG00000026207
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CNTFENSG00000242689Homo sapiens
 CntfENSMUSG00000079415Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000151  Ciliary neurotrophic factor, CNTF
 IPR009079  Four-helical cytokine-like, core


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0040007 growth IEA
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0046533 negative regulation of photoreceptor cell differentiation IEA
 biological_processGO:0046668 regulation of retinal cell programmed cell death IEA
 biological_processGO:0048143 astrocyte activation IBA
 biological_processGO:0048644 muscle organ morphogenesis IEA
 biological_processGO:0048666 neuron development IEA
 biological_processGO:0048680 positive regulation of axon regeneration IBA
 biological_processGO:0070120 ciliary neurotrophic factor-mediated signaling pathway IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0030424 axon IBA
 cellular_componentGO:0097058 CRLF-CLCF1 complex IEA
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005127 ciliary neurotrophic factor receptor binding IBA
 molecular_functionGO:0005138 interleukin-6 receptor binding IEA
 molecular_functionGO:0008083 growth factor activity IBA


Pathways (from Reactome)
Pathway description
IL-6-type cytokine receptor ligand interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000014716 IL6ST / interleukin 6 signal transducer / P40189* / Q00560* / Interleukin-6 receptor subunit beta *  / complex / reaction
 ENSGALG00000011031 JAK1 / tyrosine-protein kinase JAK1 / P23458* / Janus kinase 1*  / complex / reaction
 ENSGALG00000015027 JAK2 / Janus kinase 2 / O60674*  / complex / reaction






 

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