ENSGALG00000026820


Gallus gallus

Features
Gene ID: ENSGALG00000026820
  
Biological name :RNF146
  
Synonyms : ring finger protein 146 / RNF146
  
Possible biological names infered from orthology : Q9CZW6 / Q9NTX7
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 59406315
Gene end: 59407373
  
Corresponding Affymetrix probe sets: Gga.9994.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000040768
NCBI entrez gene - 425313     See in Manteia.
RefSeq - XM_015284444
RefSeq - XM_015284445
RefSeq - XM_015284446
RefSeq - XM_423089
RefSeq - XM_015284443
swissprot - R4GFH6
Ensembl - ENSGALG00000026820
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnf146ENSDARG00000089981Danio rerio
 Q9NTX7ENSG00000118518Homo sapiens
 Q9CZW6ENSMUSG00000038876Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR004170  WWE domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR018123  WWE domain, subgroup
 IPR033509  E3 ubiquitin-protein ligase RNF146


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0051865 protein autoubiquitination IEA
 biological_processGO:0070936 protein K48-linked ubiquitination IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA
 molecular_functionGO:0072572 poly-ADP-D-ribose binding IEA


Pathways (from Reactome)
Pathway description
TCF dependent signaling in response to WNT
Degradation of AXIN
Ub-specific processing proteases
Regulation of PTEN stability and activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000014614 TNKS2 / tankyrase-2 / Q3UES3* / Q9H2K2*  / complex / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction
 ENSGALG00000043164 TNKS / tankyrase-1 / O95271* / Q6PFX9* / tankyrase* / tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase*  / complex / reaction
 ENSGALG00000029402 AXIN1 / O15169*  / complex / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr