ENSGALG00000027835


Gallus gallus
proteinactivityPCBD1dehydratasetranscriptiondna-templatedprocessphenylalaninepterinalphacarbinolamineregulationtetrahydrobiopterinbiosynthetichomotetramerizationheterooligomerizationoxidation-reductionnucleusnucleoplasmcytoplasmcytosol-monooxygenase-alpha-hydroxytetrahydrobiopterinlyaseidenticalbindingtyrosinecatabolism

Features
Gene ID: ENSGALG00000027835
  
Biological name :PCBD1
  
Synonyms : O73930 / PCBD1 / Pterin-4-alpha-carbinolamine dehydratase
  
Possible biological names infered from orthology : P61457 / P61458 / pterin-4 alpha-carbinolamine dehydratase 1
  
Species: Gallus gallus
  
Chr. number: 6
Strand: -1
Band:
Gene start: 11616749
Gene end: 11620702
  
Corresponding Affymetrix probe sets: Gga.427.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051616
Ensembl peptide - ENSGALP00000043457
NCBI entrez gene - 395729     See in Manteia.
RefSeq - NM_204905
RefSeq Peptide - NP_990236
swissprot - O73930
swissprot - A0A1D5PFP9
Ensembl - ENSGALG00000027835
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pcbd1ENSDARG00000031981Danio rerio
 PCBD1ENSG00000166228Homo sapiens
 Pcbd1ENSMUSG00000020098Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PCBD2 / pterin-4-alpha-carbinolamine dehydratase 2 / Q9CZL5* / Q9H0N5*ENSGALG0000000636763


Protein motifs (from Interpro)
Interpro ID Name
 IPR001533  Pterin 4 alpha carbinolamine dehydratase


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcellular component organizationcellular component biogenesisoxidation-reduction processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcellular component organizationcellular component biogenesisoxidation-reduction processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcellular component organizationcellular component biogenesisoxidation-reduction processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcellular component organizationcellular component biogenesisoxidation-reduction processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcellular component organizationcellular component biogenesisoxidation-reduction processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcellular component organizationcellular component biogenesisoxidation-reduction processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcellular component organizationcellular component biogenesisoxidation-reduction processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcellular component organizationcellular component biogenesisoxidation-reduction processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcellular component organizationcellular component biogenesisoxidation-reduction processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcellular component organizationcellular component biogenesisoxidation-reduction processnitrogen compounitrogen compound metabolic processbiosynthetic prbiosynthetic processcellular metabocellular metabolic processprimary metabolprimary metabolic processorganic substanorganic substance metabolic processsmall molecule small molecule metabolic processcellular componcellular component organizationcellular componcellular component biogenesisoxidation-reducoxidation-reduction process
oxidoreductase activitylyase activityprotein bindingoxidoreductase activitylyase activityprotein bindingoxidoreductase activitylyase activityprotein bindingoxidoreductase activitylyase activityprotein bindingoxidoreductase activitylyase activityprotein bindingoxidoreductase activitylyase activityprotein bindingoxidoreductase activitylyase activityprotein bindingoxidoreductase activitylyase activityprotein bindingoxidoreductase activitylyase activityprotein bindingoxidoreductase activitylyase activityprotein bindingoxidoreductase activityoxidoreductase activitylyase activitylyase activityprotein bindingprotein binding
cellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006729 tetrahydrobiopterin biosynthetic process IEA
 biological_processGO:0051289 protein homotetramerization IEA
 biological_processGO:0051291 protein heterooligomerization IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004505 phenylalanine 4-monooxygenase activity IEA
 molecular_functionGO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Phenylalanine and tyrosine catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000027835 PCBD1 / O73930 / Pterin-4-alpha-carbinolamine dehydratase / P61458* / P61457* / pterin-4 alpha-carbinolamine dehydratase 1*  / complex






 

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