ENSGALG00000028483


Gallus gallus

Features
Gene ID: ENSGALG00000028483
  
Biological name :NKX2-8
  
Synonyms : NK2 homeobox 8 / NKX2-8
  
Possible biological names infered from orthology : Homeobox protein Nkx-2.8 / Nkx2-9 / O15522 / O70584
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 36718028
Gene end: 36719677
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000042165
NCBI entrez gene - 771397     See in Manteia.
RefSeq - XM_003641360
swissprot - R4GJ61
Ensembl - ENSGALG00000028483
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NKX2-8ENSG00000136327Homo sapiens
 Nkx2-9ENSMUSG00000058669Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NKX2-2 / NK2 homeobox 2 / O95096* / P42586*ENSGALG0000003686947
NKX2-1 / homeobox protein Nkx-2.1 ENSGALG0000003763234
NKX2-3 / NK2 homeobox 3 / P97334* / Q8TAU0* / Homeobox protein Nkx-2.3 *ENSGALG0000003093233
NKX2-5 / homeobox protein Nkx-2.5 ENSGALG0000000288631
NKX2-6 / homeobox protein Nkx-2.6 ENSGALG0000000036529
NKX2-4 / NK2 homeobox 4 / Q9EQM3* / Q9H2Z4* / Homeobox protein Nkx-2.4 *ENSGALG0000003583529
NKX3-2 / homeobox protein Nkx-3.2 / P78367* / P97503* / NK3 homeobox 2*ENSGALG0000003185925
HMX3 / homeobox protein HMX3 / A6NHT5* / P42581* / H6 family homeobox 3*ENSGALG0000002341520
HMX2 / H6 family homeobox 2 / A2RU54* / P43687* / Homeobox protein HMX2 *ENSGALG0000003087519
SOHO-1 / sensory organ homeobox protein SOHo / HMX1* / O70218* / Q9NP08* / H6 family homeobox 1* / Homeobox protein HMX1 *ENSGALG0000001559918
HMX1 / homeobox protein HMX1 ENSGALG0000004206218


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007409 axonogenesis IEA
 biological_processGO:0030323 respiratory tube development IEA
 biological_processGO:0030324 lung development IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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