Manteia

ENSGALG00000029940

Gallus gallus

Features

Gene ID:	ENSGALG00000029940

Biological name :	IL1B

Synonyms :	IL1B / interleukin 1 beta

Possible biological names infered from orthology :	P01584 / P10749

Species:	Gallus gallus

Chr. number:	22
Strand:	-1
Band:
Gene start:	4616890
Gene end:	4618940

Corresponding Affymetrix probe sets:	Gga.19.1.S1_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000050171 Ensembl peptide - ENSGALP00000047706 NCBI entrez gene - 395196 See in Manteia. RefSeq - XM_015297469 RefSeq - NM_204524 RefSeq Peptide - NP_989855 swissprot - O73909 swissprot - A0A1D5P4U4 Ensembl - ENSGALG00000029940

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name

Similarity(%)

No match

Protein motifs (from Interpro)

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001660	fever generation	IEA
biological_process	GO:0002224	toll-like receptor signaling pathway	TAS
biological_process	GO:0002232	leukocyte chemotaxis involved in inflammatory response	TAS
biological_process	GO:0002269	leukocyte activation involved in inflammatory response	TAS
biological_process	GO:0006953	acute-phase response	ISS
biological_process	GO:0006954	inflammatory response	IEA
biological_process	GO:0006955	immune response	IEA
biological_process	GO:0009615	response to virus	IEP
biological_process	GO:0010469	regulation of signaling receptor activity	IEA
biological_process	GO:0019953	sexual reproduction	TAS
biological_process	GO:0032497	detection of lipopolysaccharide	TAS
biological_process	GO:0032602	chemokine production	TAS
biological_process	GO:0043400	cortisol secretion	IDA
biological_process	GO:0050729	positive regulation of inflammatory response	TAS
biological_process	GO:0051781	positive regulation of cell division	IEA
biological_process	GO:0070417	cellular response to cold	IEP
cellular_component	GO:0005576	extracellular region	IEA
cellular_component	GO:0005615	extracellular space	IEA
cellular_component	GO:0005829	cytosol	IEA
molecular_function	GO:0005125	cytokine activity	IEA
molecular_function	GO:0005149	interleukin-1 receptor binding	IEA

Pathways (from Reactome)

Pathway description

Interleukin-1 processing

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSGALG00000001049	CASP1* / CASP4* / CASP5* / Q6UXS9* / CASP12* / O08736* / P29452* / P29466* / P49662* / P51878* / P70343* / caspase 4* / caspase 1* / caspase 5* / Caspase-12 * / caspase 12 (gene/pseudogene)...	/ reaction
ENSGALG00000007932	TRAF6 / TNF receptor associated factor 6 / P70196* / Q9Y4K3*	/ complex / reaction
ENSGALG00000009586	IRAK4 / interleukin-1 receptor-associated kinase 4 / Q8R4K2* / Q9NWZ3*	/ complex / reaction
ENSGALG00000005947	MYD88 / A5HNF6 / Myeloid differentiation primary response protein MyD88 / Q99836* / P22366* / myeloid differentiation primary response 88* / myeloid differentiation primary response gene 88*	/ complex / reaction
ENSGALG00000007253	IL1RAP / interleukin 1 receptor accessory protein / Q61730* / Q9NPH3*	/ complex / reaction
ENSGALG00000043044	IL1R1 / interleukin-1 receptor type 1 precursor / P14778* / P13504* / interleukin 1 receptor type 1* / Interleukin-1 receptor type 1 Interleukin-1 receptor type 1, membrane form Interleuki...	/ complex / reaction
ENSGALG00000030526	IL1R1* / P13504* / P14778* / interleukin 1 receptor type 1* / Interleukin-1 receptor type 1 Interleukin-1 receptor type 1, membrane form Interleukin-1 receptor type 1, soluble form*	/ complex / reaction

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr