ENSGALG00000029996


Gallus gallus

Features
Gene ID: ENSGALG00000029996
  
Biological name :PPP2R5C
  
Synonyms : PPP2R5C / serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
  
Possible biological names infered from orthology : protein phosphatase 2, regulatory subunit B, gamma / protein phosphatase 2 regulatory subunit Bgamma / Q13362 / Q60996
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 49461041
Gene end: 49507757
  
Corresponding Affymetrix probe sets: Gga.17571.1.S1_at (Chicken Array)   Gga.8903.1.S1_at (Chicken Array)   Gga.8903.2.S1_s_at (Chicken Array)   GgaAffx.23509.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046266
Ensembl peptide - ENSGALP00000063206
Ensembl peptide - ENSGALP00000062937
NCBI entrez gene - 423460     See in Manteia.
RefSeq - NM_001079482
RefSeq - XM_015287475
RefSeq Peptide - NP_001072950
swissprot - A0A1L1RWJ2
swissprot - A0A1L1RVT0
swissprot - A0A1D5P0T7
Ensembl - ENSGALG00000029996
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppp2r5caENSDARG00000059083Danio rerio
 ppp2r5cbENSDARG00000031200Danio rerio
 Q13362ENSG00000078304Homo sapiens
 Q60996ENSMUSG00000017843Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PPP2R5D / protein phosphatase 2 regulatory subunit Bdelta / Q14738* / protein phosphatase 2, regulatory subunit B, delta*ENSGALG0000004000576
PPP2R5A / protein phosphatase 2 regulatory subunit Balpha / Q15172* / Q6PD03* / protein phosphatase 2, regulatory subunit B, alpha*ENSGALG0000000982858
PPP2R5E / protein phosphatase 2 regulatory subunit Bepsilon / Q16537* / Q61151* / protein phosphatase 2, regulatory subunit B, epsilon*ENSGALG0000001184058
ENSGALG0000004607127


Protein motifs (from Interpro)
Interpro ID Name
 IPR002554  Protein phosphatase 2A, regulatory B subunit, B56
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 cellular_componentGO:0000159 protein phosphatase type 2A complex IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0019888 protein phosphatase regulator activity IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Degradation of beta-catenin by the destruction complex
Beta-catenin phosphorylation cascade
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
CTLA4 inhibitory signaling
Disassembly of the destruction complex and recruitment of AXIN to the membrane
RHO GTPases Activate Formins
RAF activation
Negative regulation of MAPK pathway
Regulation of TP53 Degradation
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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