ENSGALG00000009828


Gallus gallus

Features
Gene ID: ENSGALG00000009828
  
Biological name :PPP2R5A
  
Synonyms : PPP2R5A / protein phosphatase 2 regulatory subunit Balpha
  
Possible biological names infered from orthology : protein phosphatase 2, regulatory subunit B, alpha / Q15172 / Q6PD03
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 21979873
Gene end: 22019527
  
Corresponding Affymetrix probe sets: Gga.5852.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000015963
NCBI entrez gene - 421372     See in Manteia.
RefSeq - XM_419432
swissprot - E1C5A3
Ensembl - ENSGALG00000009828
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppp2r5aENSDARG00000027017Danio rerio
 Q15172ENSG00000066027Homo sapiens
 Q6PD03ENSMUSG00000026626Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PPP2R5E / protein phosphatase 2 regulatory subunit Bepsilon / Q16537* / Q61151* / protein phosphatase 2, regulatory subunit B, epsilon*ENSGALG0000001184075
PPP2R5C / serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform / Q13362* / Q60996* / protein phosphatase 2 regulatory subunit Bgamma* / protein phosphatase 2, re...ENSGALG0000002999663
PPP2R5D / protein phosphatase 2 regulatory subunit Bdelta / Q14738* / protein phosphatase 2, regulatory subunit B, delta*ENSGALG0000004000561
ENSGALG0000004607125


Protein motifs (from Interpro)
Interpro ID Name
 IPR002554  Protein phosphatase 2A, regulatory B subunit, B56
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0035307 positive regulation of protein dephosphorylation IEA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0090219 negative regulation of lipid kinase activity IEA
 biological_processGO:1903077 negative regulation of protein localization to plasma membrane IEA
 cellular_componentGO:0000159 protein phosphatase type 2A complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0031430 M band IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0019888 protein phosphatase regulator activity IEA
 molecular_functionGO:0019900 kinase binding IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Degradation of beta-catenin by the destruction complex
Beta-catenin phosphorylation cascade
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
CTLA4 inhibitory signaling
Disassembly of the destruction complex and recruitment of AXIN to the membrane
RHO GTPases Activate Formins
RAF activation
Negative regulation of MAPK pathway
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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