ENSGALG00000031348


Gallus gallus

Features
Gene ID: ENSGALG00000031348
  
Biological name :SPPL2A
  
Synonyms : signal peptide peptidase-like 2A precursor / SPPL2A
  
Possible biological names infered from orthology : Q8TCT8 / Q9JJF9 / signal peptide peptidase like 2A
  
Species: Gallus gallus
  
Chr. number: 10
Strand: 1
Band:
Gene start: 10733680
Gene end: 10761449
  
Corresponding Affymetrix probe sets: Gga.11672.1.S1_at (Chicken Array)   Gga.9215.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044038
Ensembl peptide - ENSGALP00000056643
Ensembl peptide - ENSGALP00000054082
NCBI entrez gene - 415450     See in Manteia.
RefSeq - NM_001012769
RefSeq Peptide - NP_001012787
swissprot - A0A1D5PUN9
swissprot - A0A1D5PMK3
swissprot - A0A1D5NUM0
Ensembl - ENSGALG00000031348
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q8TCT8ENSG00000138600Homo sapiens
 Q9JJF9ENSMUSG00000027366Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SPPL2B / signal peptide peptidase-like 2B precursor / Q3TD49* / Q8TCT7* / signal peptide peptidase like 2B*ENSGALG0000000043048
HM13 / histocompatibility minor 13 / H13* / Q8TCT9* / Q9D8V0* / Minor histocompatibility antigen H13 *ENSGALG0000000620716
SPPL3 / signal peptide peptidase like 3 / Q8TCT6* / Q9CUS9*ENSGALG0000000697916


Protein motifs (from Interpro)
Interpro ID Name
 IPR003137  PA domain
 IPR006639  Presenilin/signal peptide peptidase
 IPR007369  Peptidase A22B, signal peptide peptidase
 IPR033151  Signal peptide peptidase-like 2a


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006509 membrane protein ectodomain proteolysis IEA
 biological_processGO:0031293 membrane protein intracellular domain proteolysis IEA
 biological_processGO:0033619 membrane protein proteolysis IEA
 biological_processGO:0050776 regulation of immune response IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030660 Golgi-associated vesicle membrane IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane IEA
 cellular_componentGO:0071556 integral component of lumenal side of endoplasmic reticulum membrane IEA
 molecular_functionGO:0004190 aspartic-type endopeptidase activity IEA
 molecular_functionGO:0042500 aspartic endopeptidase activity, intramembrane cleaving IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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