ENSGALG00000032664


Gallus gallus

Features
Gene ID: ENSGALG00000032664
  
Biological name :UBE2B
  
Synonyms : UBE2B / ubiquitin conjugating enzyme E2 B
  
Possible biological names infered from orthology : P63146 / P63147
  
Species: Gallus gallus
  
Chr. number: 13
Strand: -1
Band:
Gene start: 15945884
Gene end: 15953806
  
Corresponding Affymetrix probe sets: Gga.5344.1.S1_at (Chicken Array)   GgaAffx.21945.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000043832
Ensembl peptide - ENSGALP00000044240
NCBI entrez gene - 100857678     See in Manteia.
RefSeq - XM_015294094
swissprot - A0A1D5NU23
swissprot - A0A1D5NV67
Ensembl - ENSGALG00000032664
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 UBE2BENSG00000119048Homo sapiens
 Ube2bENSMUSG00000020390Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
UBE2A / ubiquitin conjugating enzyme E2 A / P49459* / Q9Z255*ENSGALG0000000864895


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR023313  Ubiquitin-conjugating enzyme, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006301 postreplication repair IEA
 biological_processGO:0006344 maintenance of chromatin silencing IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0006513 protein monoubiquitination IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007288 sperm axoneme assembly IEA
 biological_processGO:0009411 response to UV IEA
 biological_processGO:0010845 positive regulation of reciprocal meiotic recombination IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0031056 regulation of histone modification IEA
 biological_processGO:0033128 negative regulation of histone phosphorylation IEA
 biological_processGO:0033522 histone H2A ubiquitination IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0043951 negative regulation of cAMP-mediated signaling IEA
 biological_processGO:0045141 meiotic telomere clustering IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0051026 chiasma assembly IEA
 biological_processGO:0051865 protein autoubiquitination IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:0070076 histone lysine demethylation IEA
 biological_processGO:0070193 synaptonemal complex organization IEA
 biological_processGO:0070534 protein K63-linked ubiquitination IEA
 biological_processGO:0070936 protein K48-linked ubiquitination IEA
 biological_processGO:0070979 protein K11-linked ubiquitination IEA
 cellular_componentGO:0000785 chromatin IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0001741 XY body IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005657 replication fork IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0033503 HULC complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0061631 ubiquitin conjugating enzyme activity IEA


Pathways (from Reactome)
Pathway description
Recognition of DNA damage by PCNA-containing replication complex
E3 ubiquitin ligases ubiquitinate target proteins
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000028133 UBE2V2 / Q5F3Z3 / Ubiquitin-conjugating enzyme E2 variant 2 / Q9D2M8* / Q15819* / ubiquitin conjugating enzyme E2 V2*  / complex / reaction
 ENSGALG00000029292 PCNA / Q9DEA3 / Proliferating cell nuclear antigen / P17918* / P12004* / Pcna-ps2*  / complex / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex / reaction
 ENSGALG00000000734 RPA2 / RPA4* / Q13156* / P15927* / replication protein A2* / replication protein A4*  / complex / reaction
 ENSGALG00000003072 RPA1 / Q5ZJJ2 / Replication protein A 70 kDa DNA-binding subunit / Q8VEE4* / P27694* / replication protein A1*  / complex / reaction
 ENSGALG00000010700 RPA3 / replication protein A3 / P35244* / Q9CQ71* / Replication protein A 14 kDa subunit *  / complex / reaction
 ENSGALG00000012289 SHPRH / SNF2 histone linker PHD RING helicase / Q149N8* / Q7TPQ3* / E3 ubiquitin-protein ligase SHPRH *  / complex / reaction
 ENSGALG00000032664 UBE2B / ubiquitin conjugating enzyme E2 B / P63146* / P63147*  / complex






 

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