ENSGALG00000032819


Gallus gallus

Features
Gene ID: ENSGALG00000032819
  
Biological name :RNF41
  
Synonyms : ring finger protein 41 / RNF41
  
Possible biological names infered from orthology : E3 ubiquitin-protein ligase NRDP1 / Q8BH75 / Q9H4P4
  
Species: Gallus gallus
  
Chr. number: 33
Strand: -1
Band:
Gene start: 704180
Gene end: 711674
  
Corresponding Affymetrix probe sets: Gga.11263.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050940
NCBI entrez gene - 426468     See in Manteia.
RefSeq - XM_015300300
RefSeq - XM_015300301
swissprot - A0A1D5PDU4
Ensembl - ENSGALG00000032819
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnf41ENSDARG00000036831Danio rerio
 RNF41ENSG00000181852Homo sapiens
 Rnf41ENSMUSG00000025373Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q2KHN1* / Q9CQ29* / RNF151* / ring finger protein 151*ENSGALG0000003480325


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR008974  TRAF-like
 IPR013010  Zinc finger, SIAH-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR015036  E3 ubiquitin-protein ligase NRDP1
 IPR017907  Zinc finger, RING-type, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0010498 proteasomal protein catabolic process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0043408 regulation of MAPK cascade IEA
 biological_processGO:0045619 regulation of lymphocyte differentiation IEA
 biological_processGO:0045637 regulation of myeloid cell differentiation IEA
 biological_processGO:0045732 positive regulation of protein catabolic process IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0051865 protein autoubiquitination IEA
 biological_processGO:0051896 regulation of protein kinase B signaling IEA
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IEA
 biological_processGO:1901525 negative regulation of mitophagy IEA
 biological_processGO:2000114 regulation of establishment of cell polarity IEA
 biological_processGO:2000377 regulation of reactive oxygen species metabolic process IEA
 biological_processGO:2000379 positive regulation of reactive oxygen species metabolic process IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0071782 endoplasmic reticulum tubular network IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005128 erythropoietin receptor binding IEA
 molecular_functionGO:0005135 interleukin-3 receptor binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0017160 Ral GTPase binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0030971 receptor tyrosine kinase binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
Downregulation of ERBB2:ERBB3 signaling
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000015422 NRG1 / pro-neuregulin-1, membrane-bound isoform / Q02297* / neuregulin 1*  / complex / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex / reaction
 ENSGALG00000033641 NRG2 / neuregulin 2 / O14511*  / complex / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex / reaction
 ENSGALG00000031529 ERBB2 / receptor tyrosine-protein kinase erbB-2 precursor / P04626* / P70424* / erb-b2 receptor tyrosine kinase 2* / Receptor tyrosine-protein kinase erbB-2 *  / complex / reaction
 ENSGALG00000005894 USP8 / ubiquitin specific peptidase 8 / P40818* / Q80U87*  / complex / reaction






 

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