ENSGALG00000033391


Gallus gallus

Features
Gene ID: ENSGALG00000033391
  
Biological name :ISL2
  
Synonyms : ISL2 / ISL LIM homeobox 2
  
Possible biological names infered from orthology : Insulin enhancer protein ISL-2 / Q96A47 / Q9CXV0
  
Species: Gallus gallus
  
Chr. number: 10
Strand: -1
Band:
Gene start: 3288896
Gene end: 3291190
  
Corresponding Affymetrix probe sets: Gga.790.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051615
Ensembl peptide - ENSGALP00000055627
NCBI entrez gene - 396382     See in Manteia.
RefSeq - XM_015279024
RefSeq - XM_015279026
RefSeq - XM_015279027
swissprot - A0A1D5PRU8
swissprot - A0A1D5PFP8
Ensembl - ENSGALG00000033391
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 isl2aENSDARG00000003971Danio rerio
 isl2bENSDARG00000053499Danio rerio
 ISL2ENSG00000159556Homo sapiens
 Isl2ENSMUSG00000032318Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ISL1 / P50211 / Insulin gene enhancer protein ISL-1 / P61372* / P61371* / ISL LIM homeobox 1* / Insulin enhancer protein ISL-1 *ENSGALG0000001488442
LMX1B / P53413 / LIM/homeobox protein LMX-1.2 / O60663* / LIM homeobox transcription factor 1 beta*ENSGALG0000004058217
LMX1A / LIM homeobox transcription factor 1 alpha / Q8TE12* / Q9JKU8*ENSGALG0000000342416
LHX3 / LIM/homeobox protein Lhx3 / Q9UBR4* / P50481* / LIM homeobox 3* / LIM homeobox protein 3*ENSGALG0000000392816
LHX1 / LIM/homeobox protein Lhx1 / P48742* / P63006* / LIM homeobox 1*ENSGALG0000000540916
LHX9 / LIM/homeobox protein Lhx9 / Q9NQ69* / Q9WUH2* / LIM homeobox 9*ENSGALG0000000222315
LHX5 / Gallus gallus LIM homeobox 5 (LHX5), mRNA. / P61375* / Q9H2C1* / LIM homeobox 5* / LIM homeobox protein 5*ENSGALG0000000830315
LHX4 / LIM homeobox 4 / P53776* / Q969G2* / LIM/homeobox protein Lhx4 *ENSGALG0000003658715
LHX2 / LIM/homeobox protein Lhx2 ENSGALG0000000112414
LHX8 / LIM/homeobox protein Lhx8 / O35652* / Q68G74* / LIM homeobox 8*ENSGALG0000001136913
LHX6 / LIM homeobox 6 / Q9R1R0* / Q9UPM6* / Mus musculus LIM homeobox protein 6 (Lhx6), transcript variant 5, mRNA.*ENSGALG0000000134712
LMO4 / LIM domain only 4 / P61968* / P61969* / LIM domain transcription factor LMO4 *ENSGALG000000062528
ENSGALG000000356796
LMO3 / LIM domain only 3 / Q8BZL8* / Q8TAP4* / Mus musculus LIM domain only 3 (Lmo3), transcript variant 2, mRNA.*ENSGALG000000363586
LMO2 / LIM domain only 2 / P25791* / P25801* / Rhombotin-2 *ENSGALG000000298925


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR001781  Zinc finger, LIM-type
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0021520 spinal cord motor neuron cell fate specification IEA
 biological_processGO:0021524 visceral motor neuron differentiation IEA
 biological_processGO:0031290 retinal ganglion cell axon guidance IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0048663 neuron fate commitment IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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