ENSGALG00000034210


Gallus gallus

Features
Gene ID: ENSGALG00000034210
  
Biological name :RPTOR
  
Synonyms : regulatory associated protein of MTOR complex 1 / RPTOR
  
Possible biological names infered from orthology : Q8N122
  
Species: Gallus gallus
  
Chr. number: 18
Strand: -1
Band:
Gene start: 9437300
Gene end: 9553969
  
Corresponding Affymetrix probe sets: Gga.18621.1.S1_s_at (Chicken Array)   Gga.7508.2.S1_at (Chicken Array)   GgaAffx.20302.1.S1_s_at (Chicken Array)   GgaAffx.22109.1.S1_s_at (Chicken Array)   GgaAffx.22109.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045359
Ensembl peptide - ENSGALP00000055683
Ensembl peptide - ENSGALP00000048160
Ensembl peptide - ENSGALP00000047335
Ensembl peptide - ENSGALP00000045585
NCBI entrez gene - 428674     See in Manteia.
RefSeq - XM_426232
RefSeq - XM_004946273
RefSeq - XM_015295611
RefSeq - XM_015295612
RefSeq - XM_015295613
RefSeq - XM_015295614
swissprot - A0A1D5P636
swissprot - A0A1D5P3T0
swissprot - A0A1D5NYX4
swissprot - A0A1D5NYA2
swissprot - A0A1D5PS04
Ensembl - ENSGALG00000034210
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rptorENSDARG00000098726Danio rerio
 RPTORENSG00000141564Homo sapiens
 RptorENSMUSG00000025583Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000357  HEAT repeat
 IPR001680  WD40 repeat
 IPR004083  Regulatory associated protein of TOR
 IPR011989  Armadillo-like helical
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016024  Armadillo-type fold
 IPR017986  WD40-repeat-containing domain
 IPR029347  Raptor, N-terminal CASPase-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0008361 regulation of cell size IEA
 biological_processGO:0010800 positive regulation of peptidyl-threonine phosphorylation IEA
 biological_processGO:0030307 positive regulation of cell growth IEA
 biological_processGO:0031669 cellular response to nutrient levels IEA
 biological_processGO:0031929 TOR signaling IEA
 biological_processGO:0032008 positive regulation of TOR signaling IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0038202 TORC1 signaling IEA
 biological_processGO:0045945 positive regulation of transcription by RNA polymerase III IEA
 biological_processGO:0071230 cellular response to amino acid stimulus IEA
 biological_processGO:0071233 cellular response to leucine IEA
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity IEA
 biological_processGO:1900087 positive regulation of G1/S transition of mitotic cell cycle IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0010494 cytoplasmic stress granule IEA
 cellular_componentGO:0031931 TORC1 complex IEA
 molecular_functionGO:0001030 RNA polymerase III type 1 promoter DNA binding IEA
 molecular_functionGO:0001031 RNA polymerase III type 2 promoter DNA binding IEA
 molecular_functionGO:0001032 RNA polymerase III type 3 promoter DNA binding IEA
 molecular_functionGO:0001156 TFIIIC-class transcription factor binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0030291 protein serine/threonine kinase inhibitor activity IEA
 molecular_functionGO:0030295 protein kinase activator activity IEA
 molecular_functionGO:0030674 protein binding, bridging IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0071889 14-3-3 protein binding IEA


Pathways (from Reactome)
Pathway description
Macroautophagy
mTOR signalling
mTORC1-mediated signalling
HSF1-dependent transactivation
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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