ENSDARG00000098726


Danio rerio

Features
Gene ID: ENSDARG00000098726
  
Biological name :rptor
  
Synonyms : regulatory associated protein of MTOR, complex 1 / rptor
  
Possible biological names infered from orthology : Q8N122
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 17725788
Gene end: 17999776
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000132117
Ensembl peptide - ENSDARP00000154260
Ensembl peptide - ENSDARP00000154154
Ensembl peptide - ENSDARP00000130300
NCBI entrez gene - 560455     See in Manteia.
swissprot - A0A0R4IFI0
swissprot - A0A0R4IAI4
ZFIN ID - ZDB-GENE-130530-685
Ensembl - ENSDARG00000098726
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RPTORENSGALG00000034210Gallus gallus
 RPTORENSG00000141564Homo sapiens
 RptorENSMUSG00000025583Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000357  HEAT repeat
 IPR001680  WD40 repeat
 IPR004083  Regulatory associated protein of TOR
 IPR011989  Armadillo-like helical
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016024  Armadillo-type fold
 IPR017986  WD40-repeat-containing domain
 IPR029347  Raptor, N-terminal CASPase-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031929 TOR signaling IEA
 cellular_componentGO:0031931 TORC1 complex IEA


Pathways (from Reactome)
Pathway description
Macroautophagy
mTOR signalling
mTORC1-mediated signalling
HSF1-dependent transactivation
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003167 mlst8 / Q803V5 / MTOR associated protein, LST8 homolog (S. cerevisiae) / Q9BVC4* / Q9DCJ1* / MTOR associated protein, LST8 homolog* / Target of rapamycin complex subunit LST8 *  / complex
 ENSDARG00000017537 prkag3a / protein kinase, AMP-activated, gamma 3a non-catalytic subunit / Q9UGI9* / PRKAG3* / Q8BGM7* / protein kinase AMP-activated non-catalytic subunit gamma 3* / protein kinase, AMP-act...  / reaction
 ENSDARG00000003818 prkag1 / protein kinase, AMP-activated, gamma 1 non-catalytic subunit / O54950* / P54619* / protein kinase AMP-activated non-catalytic subunit gamma 1*  / reaction
 ENSDARG00000032769 Q08BA4 / slc38a9 / solute carrier family 38, member 9 / Q8NBW4*  / complex / reaction
 ENSDARG00000046143 prkab1b / protein kinase, AMP-activated, beta 1 non-catalytic subunit, b / PRKAB1* / Q9R078* / Q9Y478* / protein kinase AMP-activated non-catalytic subunit beta 1* / protein kinase, AMP-act...  / reaction
 ENSDARG00000036040 atg13 / Q7SYE0 / ATG13 autophagy related 13 homolog (S. cerevisiae) / Q91YI1* / O75143* / autophagy related 13* / Mus musculus autophagy related 13 (Atg13), transcript variant 4, mRNA.*  / complex / reaction
 ENSDARG00000060596 prkaa1 / protein kinase, AMP-activated, alpha 1 catalytic subunit / Q13131* / Q5EG47* / protein kinase AMP-activated catalytic subunit alpha 1*  / reaction
 ENSDARG00000043287 atg101 / Q3B736 / autophagy related 101 / Q9BSB4* / Q9D8Z6* / Autophagy-related protein 101 *  / complex / reaction
 ENSDARG00000060641 prkaa2 / protein kinase, AMP-activated, alpha 2 catalytic subunit / P54646* / protein kinase AMP-activated catalytic subunit alpha 2*  / reaction
 ENSDARG00000044183 prkab1a / protein kinase, AMP-activated, beta 1 non-catalytic subunit, a / PRKAB1* / Q9R078* / Q9Y478* / protein kinase AMP-activated non-catalytic subunit beta 1* / protein kinase, AMP-act...  / reaction
 ENSDARG00000076559 rb1cc1 / RB1-inducible coiled-coil 1 / Q8TDY2*  / complex / reaction
 ENSDARG00000067817 CABZ01083448.1 / O43741* / PRKAB2* / protein kinase AMP-activated non-catalytic subunit beta 2*  / reaction
 ENSDARG00000000369 prkag3b / protein kinase, AMP-activated, gamma 3b non-catalytic subunit / Q9UGI9* / PRKAG3* / Q8BGM7* / protein kinase AMP-activated non-catalytic subunit gamma 3* / protein kinase, AMP-act...  / reaction
 ENSDARG00000074481 ulk1b / unc-51 like autophagy activating kinase 1 / ULK1* / O75385* / unc-51 like kinase 1*  / complex / reaction
 ENSDARG00000074667 akt1s1 / AKT1 substrate 1 (proline-rich) / Q96B36* / Q9D1F4* / AKT1 substrate 1* / Proline-rich AKT1 substrate 1 *  / complex / reaction
 ENSDARG00000013078 ywhaba / Q5PRD0 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a / YWHAB* / P31946* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activat...  / complex / reaction
 ENSDARG00000036489 zgc:112356 / MAF1* / Q9D0U6* / Q9H063* / MAF1 homolog, negative regulator of RNA polymerase III* / Repressor of RNA polymerase III transcription MAF1 homolog *  / reaction
 ENSDARG00000098726 rptor / regulatory associated protein of MTOR, complex 1 / Q8N122*  / complex






 

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