ENSGALG00000035752


Gallus gallus

Features
Gene ID: ENSGALG00000035752
  
Biological name :PEX2
  
Synonyms : peroxisomal biogenesis factor 2 / PEX2
  
Possible biological names infered from orthology : P28328
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 119928007
Gene end: 119951049
  
Corresponding Affymetrix probe sets: Gga.11693.1.S1_s_at (Chicken Array)   GgaAffx.11623.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000056867
NCBI entrez gene - 420192     See in Manteia.
RefSeq - XM_015282789
RefSeq - NM_001008454
RefSeq - XM_015282786
RefSeq - XM_015282788
RefSeq Peptide - NP_001008454
swissprot - Q5ZM64
Ensembl - ENSGALG00000035752
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pex2ENSDARG00000062421Danio rerio
 PEX2ENSG00000164751Homo sapiens
 Pex2ENSMUSG00000040374Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR006845  Pex, N-terminal
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR018957  Zinc finger, C3HC4 RING-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000038 very long-chain fatty acid metabolic process IEA
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006635 fatty acid beta-oxidation IEA
 biological_processGO:0007031 peroxisome organization IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0016558 protein import into peroxisome matrix IEA
 biological_processGO:0031648 protein destabilization IEA
 biological_processGO:0048147 negative regulation of fibroblast proliferation IEA
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005779 integral component of peroxisomal membrane IEA
 cellular_componentGO:0016593 Cdc73/Paf1 complex IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
E3 ubiquitin ligases ubiquitinate target proteins
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002151 PEX12 / peroxisomal biogenesis factor 12 / O00623* / Q8VC48* / Peroxisome assembly protein 12 *  / complex
 ENSGALG00000002836 PEX14 / peroxisomal biogenesis factor 14 / O75381* / Q9R0A0* / Peroxisomal membrane protein PEX14 *  / complex
 ENSGALG00000007832 PEX13 / peroxisomal biogenesis factor 13 / Q92968* / Q9D0K1* / Peroxisomal membrane protein PEX13 *  / complex
 ENSGALG00000005860 ACAA1 / acetyl-CoA acyltransferase 1 / Q921H8* / Acaa1a* / Acaa1b* / P09110* / Q8VCH0* / acetyl-Coenzyme A acyltransferase 1B* / acetyl-Coenzyme A acyltransferase 1A*  / complex
 ENSGALG00000006505 ZFAND6 / zinc finger AN1-type containing 6 / Q6FIF0* / Q9DCH6* / zinc finger, AN1-type domain 6*  / complex / reaction
 ENSGALG00000021213 UBE2D1 / ubiquitin conjugating enzyme E2 D1 / P51668* / P61080*  / complex / reaction
 ENSGALG00000013874 PEX7 / peroxisomal biogenesis factor 7 / O00628* / P97865* / Peroxisomal targeting signal 2 receptor *  / complex
 ENSGALG00000009410 PEX1 / peroxisomal biogenesis factor 1 / O43933* / Q5BL07* / Peroxisome biosis factor 1 *  / complex / reaction
 ENSGALG00000009236 AGPS / alkylglycerone phosphate synthase / O00116*  / complex
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex / reaction
 ENSGALG00000038128 UBE2D2 / ubiquitin conjugating enzyme E2 D2 / P62838* / P62837* / Ube2d2a* / ubiquitin-conjugating enzyme E2D 2A*  / complex / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex / reaction
 ENSGALG00000035636 PHYH / phytanoyl-CoA 2-hydroxylase / O14832* / O35386* / phytanoyl-CoA hydroxylase*  / complex






 

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