ENSGALG00000039200


Gallus gallus

Features
Gene ID: ENSGALG00000039200
  
Biological name :AXIN2
  
Synonyms : AXIN2
  
Possible biological names infered from orthology : O88566 / Q9Y2T1
  
Species: Gallus gallus
  
Chr. number: 18
Strand: 1
Band:
Gene start: 7687437
Gene end: 7708690
  
Corresponding Affymetrix probe sets: Gga.8363.1.S1_at (Chicken Array)   Gga.8363.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000054778
NCBI entrez gene - 395152     See in Manteia.
RefSeq - NM_204491
RefSeq Peptide - NP_989822
swissprot - A0A1D5PPH8
Ensembl - ENSGALG00000039200
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 axin2ENSDARG00000100149Danio rerio
 AXIN2ENSG00000168646Homo sapiens
 Axin2ENSMUSG00000000142Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AXIN1 / O15169*ENSGALG0000002940244


Protein motifs (from Interpro)
Interpro ID Name
 IPR001158  DIX domain
 IPR014936  Axin beta-catenin binding
 IPR016137  RGS domain
 IPR024066  RGS, subdomain 1/3
 IPR029071  Ubiquitin-like domain superfamily
 IPR032101  Axin-1/2, tankyrase-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001756 somitogenesis IEA
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0001957 intramembranous ossification IEA
 biological_processGO:0003139 secondary heart field specification IEA
 biological_processGO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition IEA
 biological_processGO:0010942 positive regulation of cell death IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030111 regulation of Wnt signaling pathway IEA
 biological_processGO:0030282 bone mineralization IEA
 biological_processGO:0032423 regulation of mismatch repair IEA
 biological_processGO:0034613 cellular protein localization IEA
 biological_processGO:0042476 odontogenesis IEA
 biological_processGO:0043570 maintenance of DNA repeat elements IEA
 biological_processGO:0045668 negative regulation of osteoblast differentiation IEA
 biological_processGO:0048255 mRNA stabilization IEA
 biological_processGO:0061181 regulation of chondrocyte development IEA
 biological_processGO:0070602 regulation of centromeric sister chromatid cohesion IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0070411 I-SMAD binding IEA


Pathways (from Reactome)
Pathway description
TCF dependent signaling in response to WNT
Degradation of AXIN
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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