Manteia

ENSGALG00000040380

Gallus gallus

Features

Gene ID:	ENSGALG00000040380

Biological name :	RAD51C

Synonyms :	RAD51C / RAD51 paralog C

Possible biological names infered from orthology :	DNA repair 3 / O43502 / Q924H5

Species:	Gallus gallus

Chr. number:	19
Strand:	1
Band:
Gene start:	7091011
Gene end:	7107494

Corresponding Affymetrix probe sets:	GgaAffx.3166.1.S1_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000048159 Ensembl peptide - ENSGALP00000063141 Ensembl peptide - ENSGALP00000062984 NCBI entrez gene - 417626 See in Manteia. RefSeq - XM_015296122 RefSeq - XM_415870 swissprot - A0A1L1RWC9 swissprot - A0A1L1RVX7 swissprot - A0A1D5P635 Ensembl - ENSGALG00000040380

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
XRCC3 / X-ray repair cross complementing 3 / O43542* / Q9CXE6* / X-ray repair complementing defective repair in Chinese hamster cells 3*	ENSGALG00000011533	22
RAD51D / RAD51 paralog D / O55230* / O75771*	ENSGALG00000031918	20
RAD51B / RAD51 paralog B / O15315* / O35719* / DNA repair 2 *	ENSGALG00000009491	18

Protein motifs (from Interpro)

Interpro ID	Name
IPR013632	DNA recombination and repair protein Rad51-like, C-terminal
IPR016467	DNA recombination and repair protein, RecA-like
IPR020588	DNA recombination and repair protein RecA-like, ATP-binding domain
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000722	telomere maintenance via recombination	IEA
biological_process	GO:0000724	double-strand break repair via homologous recombination	IEA
biological_process	GO:0006281	DNA repair	IEA
biological_process	GO:0006310	DNA recombination	IEA
biological_process	GO:0007066	female meiosis sister chromatid cohesion	IEA
biological_process	GO:0007131	reciprocal meiotic recombination	IEA
biological_process	GO:0007141	male meiosis I	IEA
biological_process	GO:0007283	spermatogenesis	IEA
biological_process	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	IEA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005657	replication fork	IEA
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005739	mitochondrion	IEA
cellular_component	GO:0005829	cytosol	IEA
cellular_component	GO:0030054	cell junction	IEA
cellular_component	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex	IEA
cellular_component	GO:0033065	Rad51C-XRCC3 complex	IEA
cellular_component	GO:0043231	intracellular membrane-bounded organelle	IEA
cellular_component	GO:0048471	perinuclear region of cytoplasm	IEA
cellular_component	GO:0048476	Holliday junction resolvase complex	IEA
molecular_function	GO:0000400	four-way junction DNA binding	IEA
molecular_function	GO:0003677	DNA binding	IEA
molecular_function	GO:0005524	ATP binding	IEA
molecular_function	GO:0008094	DNA-dependent ATPase activity	IEA
molecular_function	GO:0008821	crossover junction endodeoxyribonuclease activity	IEA

Pathways (from Reactome)

Pathway description

HDR through Homologous Recombination (HRR)

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSGALG00000006123	RTEL1* / Q0VGM9* / Q9NZ71* / RTEL1-TNFRSF6B* / RTEL1-TNFRSF6B readthrough (NMD candidate)* / regulator of telomere elongation helicase 1*	/ reaction
ENSGALG00000026865	XRCC2 / X-ray repair cross complementing 2 / O43543* / Q9CX47* / X-ray repair complementing defective repair in Chinese hamster cells 2*	/ complex / reaction
ENSGALG00000011533	XRCC3 / X-ray repair cross complementing 3 / O43542* / Q9CXE6* / X-ray repair complementing defective repair in Chinese hamster cells 3*	/ complex / reaction
ENSGALG00000017290	RAD51AP1 / RAD51 associated protein 1 / Q96B01* / RAD51-associated protein 1 isoform 2 *	/ reaction
ENSGALG00000031918	RAD51D / RAD51 paralog D / O55230* / O75771*	/ complex / reaction
ENSGALG00000031841	SLX4 / SLX4 structure-specific endonuclease subunit / Q6P1D7* / Q8IY92* / Structure-specific endonuclease subunit SLX4 *	/ reaction

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr