ENSGALG00000040672


Gallus gallus

Features
Gene ID: ENSGALG00000040672
  
Biological name :IGFBP4
  
Synonyms : IGFBP4 / insulin-like growth factor-binding protein 4 precursor
  
Possible biological names infered from orthology : insulin like growth factor binding protein 4 / P22692 / P47879
  
Species: Gallus gallus
  
Chr. number: 27
Strand: 1
Band:
Gene start: 4865485
Gene end: 4870779
  
Corresponding Affymetrix probe sets: Gga.8434.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047488
NCBI entrez gene - 374271     See in Manteia.
RefSeq - NM_204353
RefSeq Peptide - NP_989684
swissprot - A0A1D5P480
Ensembl - ENSGALG00000040672
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IGFBP4ENSG00000141753Homo sapiens
 Igfbp4ENSMUSG00000017493Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IGFBP5 / insulin like growth factor binding protein 5 / P24593* / Q07079*ENSGALG0000001146837
IGFBP1 / insulin-like growth factor-binding protein 1 precursor / P08833* / P47876* / insulin like growth factor binding protein 1*ENSGALG0000004349336
IGFBP2 / insulin-like growth factor-binding protein 2 precursor / P18065* / P47877* / insulin like growth factor binding protein 2*ENSGALG0000001146935
IGFBP3 / insulin like growth factor binding protein 3 / P17936* / P47878*ENSGALG0000003794032


Protein motifs (from Interpro)
Interpro ID Name
 IPR000716  Thyroglobulin type-1
 IPR000867  Insulin-like growth factor-binding protein, IGFBP
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR009168  Insulin-like growth factor binding protein
 IPR017891  Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site
 IPR022321  Insulin-like growth factor-binding protein family 1-6, chordata
 IPR022327  Insulin-like growth factor-binding protein 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0010906 regulation of glucose metabolic process IEA
 biological_processGO:0040008 regulation of growth IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IEA
 biological_processGO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway IEA
 biological_processGO:0044342 type B pancreatic cell proliferation IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005520 insulin-like growth factor binding IEA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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