ENSGALG00000042389


Gallus gallus

Features
Gene ID: ENSGALG00000042389
  
Biological name :EN1
  
Synonyms : EN1 / engrailed homeobox 1
  
Possible biological names infered from orthology : Homeobox protein engrailed-1 / P09065 / Q05925
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 28671050
Gene end: 28673108
  
Corresponding Affymetrix probe sets: GgaAffx.7682.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000052689
NCBI entrez gene - 771008     See in Manteia.
RefSeq - XM_001234328
swissprot - A0A1D5PIQ4
Ensembl - ENSGALG00000042389
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 en1aENSDARG00000014321Danio rerio
 en1bENSDARG00000098730Danio rerio
 EN1ENSG00000163064Homo sapiens
 En1ENSMUSG00000058665Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000004129519
VAX1 / ventral anterior homeobox 1 / Q2NKI2* / Q5SQQ9*ENSGALG0000000926115
EMX2 / empty spiracles homeobox 2 / Q04743* / Q04744* / Homeobox protein EMX2 *ENSGALG0000000930214
EMX1 / empty spiracles homeobox 1 / Q04741* / Q04742* / Homeobox protein EMX1 *ENSGALG0000003051614
NOTO / A8MTQ0* / Q5TIS6* / notochord homeobox* / Homeobox protein notochord *ENSGALG0000003598112
GNOT2 / Gallus gallus Gnot2 homeodomain protein (GNOT2), mRNA. / NOTO* / A8MTQ0* / Q5TIS6* / notochord homeobox* / Homeobox protein notochord *ENSGALG0000001058811


Protein motifs (from Interpro)
Interpro ID Name
 IPR000747  Homeobox domain engrailed
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR019549  Homeobox engrailed, C-terminal
 IPR019737  Homeobox engrailed-type, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008344 adult locomotory behavior IEA
 biological_processGO:0009953 dorsal/ventral pattern formation IEA
 biological_processGO:0009954 proximal/distal pattern formation IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0021549 cerebellum development IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0030326 embryonic limb morphogenesis IEA
 biological_processGO:0030901 midbrain development IEA
 biological_processGO:0030902 hindbrain development IEA
 biological_processGO:0030917 midbrain-hindbrain boundary development IEA
 biological_processGO:0035115 embryonic forelimb morphogenesis IEA
 biological_processGO:0035176 social behavior IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0042756 drinking behavior IEA
 biological_processGO:0043473 pigmentation IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048666 neuron development IEA
 biological_processGO:0060173 limb development IEA
 biological_processGO:0061743 motor learning IEA
 biological_processGO:1901215 negative regulation of neuron death IEA
 biological_processGO:1990403 embryonic brain development IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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