Manteia

ID	Phenotype	Definition	Genetic BG
MP:0000018	small ears	"outer ears of a smaller than normal size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Tyrp1^b/Tyrp1^b-65H Genetic Background: involves: 101/H * C3H/HeH
MP:0000026	abnormal inner ear morphology	"malformation or malfunction of any components of the labyrinth, including the semicircular canals, vestibule and cochlea" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:1776]	Show Allelic Composition: Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: Not Specified Allelic Composition: Tyrp1^B-lt/Tyrp1⁺ Genetic Background: Not Specified
MP:0000048	abnormal stria vascularis	"anomalous structure of the layer of highly vascularized pigmented granular cells on the outer wall of the cochlear duct" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Tyrp1^B-lt/Tyrp1⁺ Genetic Background: Not Specified
MP:0000371	diluted coat color	"a coat color that appears lighter in intensity or paler than normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mertk^tm1Grl/Mertk^tm1Grl,Tyro3^tm1Grl/Tyro3^tm1Grl Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Lyst^bg-slt/Lyst^bg-slt,Myo5a^d/Myo5a^d,Oca2^p/Oca2^p,Tyrp1^b/Tyrp1^b Genetic Background: involves: CT/Ch * YZ57/Ch Allelic Composition: a/a,Mlph^ln/Mlph^ln,Tyrp1^b/Tyrp1^b Genetic Background: C57L/J Allelic Composition: Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: C58 Allelic Composition: Tyrp1^B-lt/Tyrp1⁺ Genetic Background: C58 Allelic Composition: Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: Not Specified Allelic Composition: Tyrp1^B-w/Tyrp1⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^B-w/Tyrp1^b Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^B-w/Tyrp1^B-w Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: A/a,Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: Not Specified Allelic Composition: a/a,Myo5a^d/Myo5a⁺,Oca2^p/Oca2⁺,Tyrp1^B-lt/Tyrp1⁺ Genetic Background: involves: C58 * CT/Ch Allelic Composition: A/?,Lyst^bg/Lyst^bg,Tyrp1⁺/? Genetic Background: Not Specified Allelic Composition: a/a,Tyrp1^b/Tyrp1^b,wad/wad⁺ Genetic Background: Not Specified Allelic Composition: a/a,Tyrp1^b/Tyrp1^b,wad/wad Genetic Background: Not Specified Allelic Composition: Tyrp1^b-55H/Tyrp1^b-55H Genetic Background: involves: C3H/HeH Allelic Composition: Tyrp1^b-Btlr/Tyrp1^b-Btlr Genetic Background: C57BL/6J-Tyrp1^b-Btlr Allelic Composition: Tyrp1^b-2Btlr/Tyrp1^b-2Btlr Genetic Background: C57BL/6J-Tyrp1^b-2Btlr Allelic Composition: Tyrp1^b-3Btlr/Tyrp1^b-3Btlr Genetic Background: C57BL/6J-Tyrp1^b-3Btlr
MP:0000372	irregular coat pigmentation	"uneven coloration of the hair" [J:65030]	Show Allelic Composition: A/?,Lyst^bg/Lyst^bg,Tyrp1⁺/? Genetic Background: Not Specified
MP:0000423	delayed hair regrowth	"slow initiation and asynchrony of the hair growth cycle (anagen) after catagen phase " [J:61509]	Show Allelic Composition: Lyst^bg-slt/Lyst^bg-slt,Myo5a^d/Myo5a^d,Oca2^p/Oca2^p,Tyrp1^b/Tyrp1^b Genetic Background: involves: CT/Ch * YZ57/Ch
MP:0000427	abnormal hair cycle	"aberrant growth or asynchronous timing of the hair growth " [J:65302]	Show Allelic Composition: Lyst^bg-slt/Lyst^bg-slt,Myo5a^d/Myo5a^d,Oca2^p/Oca2^p,Tyrp1^b/Tyrp1^b Genetic Background: involves: CT/Ch * YZ57/Ch
MP:0000433	microcephaly	"an abnormally small head" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ythdf2^tm1.2Doca/Ythdf2^tm1.2Doca Genetic Background: B6.Cg-Ythdf2^tm1.2Doca
MP:0000440	domed skull		Show Allelic Composition: Tyrp1^b/Tyrp1^b-65H Genetic Background: involves: 101/H * C3H/HeH
MP:0000784	forebrain hypoplasia	"reduced cell number in the anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Cdk5rap2^an/Cdk5rap2^an,Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: WBB6F1
MP:0001059	optic nerve atrophy	"wasting of the second cranial nerve which is responsible for conveying visual information from the retina to the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Hoxa11^tm1Ssp/Hoxa11^tm1Ssp,Hoxd^tm3Ddu/Hoxd^tm3Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL Allelic Composition: Gpnmb^R150X/Gpnmb^R150X,Tyrp1^isa/Tyrp1^isa Genetic Background: involves: C57BL/6J * DBA/2J
MP:0001262	decreased body weight	"lower than normal average weight " [J:61295]	Show Allelic Composition: Tyrp1^b/Tyrp1^b-3CHLe Genetic Background: involves: 101/Rl * C3H/Rl
MP:0001265	reduced body size	"smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]	Show Allelic Composition: Tyrp1^b-1FCHLc/Tyrp1^b-1FCHLc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-65H Genetic Background: involves: 101/H * C3H/HeH
MP:0001322	abnormal iris morphology	"structural anomaly of the adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Gpnmb^R150X/Gpnmb^R150X Genetic Background: B6.D2-Gpnmb^R150X Allelic Composition: Gpnmb^R150X/Gpnmb^R150X,Tyrp1^b/Tyrp1^b Genetic Background: B6.D2-Tyrp1^b Gpnmb^R150X
MP:0001324	abnormal eye pigmentation	"change in the normal black pigmentation of the eye to another color, or lack of color" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: A/?,Lyst^bg/Lyst^bg,Tyrp1⁺/? Genetic Background: Not Specified Allelic Composition: a/a,Tyrp1^b/Tyrp1^b Genetic Background: Not Specified
MP:0001606	impaired hematopoiesis	"atypical process of blood cell formation with the result of fewer of these cells being formed" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:60896]	Show Allelic Composition: Cdk5rap2^an/Cdk5rap2^an,Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: WBB6F1
MP:0001922	reduced male fertility	"reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]	Show Allelic Composition: Tyrp1^b/Tyrp1^b-3CHLe Genetic Background: involves: 101/Rl * C3H/Rl
MP:0001923	reduced female fertility	"reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]	Show Allelic Composition: Tyrp1^b-1FCHLc/Tyrp1^b-1FCHLc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-3CHLe Genetic Background: involves: 101/Rl * C3H/Rl
MP:0001925	male infertility	"inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]	Show Allelic Composition: Tyrp1^b-1FCHLc/Tyrp1^b-1FCHLc Genetic Background: involves: 101/Rl * C3H/Rl
MP:0001963	abnormal hearing	"anomaly in the ability to receive auditory stimuli" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: Not Specified Allelic Composition: Tyrp1^B-lt/Tyrp1⁺ Genetic Background: Not Specified
MP:0002075	abnormal coat color	"irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: a/a,Mlph^ln/Mlph^ln,Tyrp1^b/Tyrp1^b Genetic Background: C57L/J Allelic Composition: Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: C58 Allelic Composition: Tyrp1^B-lt/Tyrp1⁺ Genetic Background: C58 Allelic Composition: Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: Not Specified Allelic Composition: Tyrp1^B-lt/Tyrp1⁺ Genetic Background: Not Specified Allelic Composition: Tyrp1^b/Tyrp1^b-11PU Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-11R30M Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-12PU Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-13DT Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-13R75M Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-173G Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-1DFiOD Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-1ETOPc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-1FBleo Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-1FCHLc/Tyrp1^b-1FCHLc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-1FCHLc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-1MLP5/Tyrp1^b-1MLP5 Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-1MLP5 Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-1OZ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-1THO-IV Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-26R60L Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-2MLP10/Tyrp1^b-2MLP10 Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-2MLP10 Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-2MLP7.5/Tyrp1^b-2MLP7.5 Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-2MLP7.5 Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-331K Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-33G Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-37DTD Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-37FrThc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-37Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-3CHLe Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-3MLPc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-3YPSc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-3YPSh Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-46UThc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-47DThWb Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-49HATh Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-4ACRg Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-51DThWb Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-55CoS Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-5CHLe Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-5CHLo/Tyrp1^b-5CHLo Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-5CHLo Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-5MLPm Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-5FBleb Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-8PUb Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-9Bleo Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-9PU Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-9R75VH Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-c/Tyrp1^b-c Genetic Background: involves: C57BL/10 * DBA/1 Allelic Composition: Tyrp1^b-cH/Tyrp1^b-cH Genetic Background: involves: 101/H * C3H/HeH * T Stock Allelic Composition: Tyrp1^b-cH/Tyrp1^b Genetic Background: involves: 101/H * C3H/HeH * T Stock Allelic Composition: Tyrp1^rgsc96/Tyrp1^rgsc96 Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl Allelic Composition: Tyrp1^rgsc101/Tyrp1^rgsc101 Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl Allelic Composition: Tyrp1^rgsc220/Tyrp1^rgsc220 Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl Allelic Composition: Tyrp1^rgsc671/Tyrp1^rgsc671 Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl Allelic Composition: Tyrp1^b/Tyrp1^rgsc671 Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl Allelic Composition: Tyrp1^rgsc799/Tyrp1^rgsc799 Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl Allelic Composition: Tyrp1^rgsc849/Tyrp1^rgsc849 Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl Allelic Composition: Tyrp1^rgsc892/Tyrp1^rgsc892 Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl Allelic Composition: Tyrp1^b-cJ/Tyrp1^b-cJ Genetic Background: involves: C57BL/6J * DBA/2J Allelic Composition: Tyrp1^b/Tyrp1^b-55H Genetic Background: involves: C3H/HeH Allelic Composition: Tyrp1^b-55H/Tyrp1^b-55H Genetic Background: involves: C3H/HeH Allelic Composition: Tyrp1^b/Tyrp1^b-65H Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: a/a,Tyrp1^b/Tyrp1^b Genetic Background: Not Specified
MP:0002102	abnormal ear morphology	"structural or developmental anomaly of any of the structures involved in the ear or vestibular system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Rag1^tm1Mom/Rag1^tm1Mom Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD Allelic Composition: Tyrp1^B-lt/Tyrp1⁺ Genetic Background: Not Specified
MP:0002166	altered tumor susceptibility/resistance	"greater than or less than the average number of tumors, usually a specific type, arising in a given strain when compared to controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mir126a^tm1.1Cjku/Mir126a^tm1.1Cjku Genetic Background: involves: 129/Sv * 129S1/Sv * C57BL/6
MP:0002630	abnormal endocochlear potential	"alterations in the electrical potential difference between the endolymphatic and perilymphatic compartments of the cochlea" [J:80917, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: Not Specified
MP:0002877	abnormal melanocyte morphology	"malformation of the cells that produce pigment " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: a/a,Mlph^ln/Mlph^ln,Tyrp1^b/Tyrp1^b Genetic Background: C57L/J Allelic Composition: a/a,Tyrp1^b/Tyrp1^b Genetic Background: Not Specified
MP:0002907	abnormal parturition	"defect in the process of labor and delivery in female animals " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Cdk5rap2^an/Cdk5rap2^an,Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: WBB6F1
MP:0002938	white spotting	"the appearance of patches of white fur" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Dmd^mdx-5Cv/Y Genetic Background: B6Ros.Cg-Dmd^mdx-5Cv
MP:0003136	yellow coat color	"amount and distribution of yellow pigment (phaeomelanin) relative to black or brown pigment (eumelanin) is increased compared to wild-type agouti" [llw2:Linda L. Washburn, Mouse Genome Informatics Curator]	Show Allelic Composition: A^y/a,Tyrp1^B-lt/? Genetic Background: Not Specified
MP:0003878	abnormal ear physiology	"anomolous function of the ear, not due to an anatomical defect" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:100987]	Show Allelic Composition: Tyrp1^B-lt/Tyrp1⁺ Genetic Background: Not Specified
MP:0004024	aneuploidy	"chromosome count is not an exact multiple of the haploid number " [llw2:Linda Washburn , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Cdk5rap2^an/Cdk5rap2^an,Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: WBB6F1
MP:0004046	abnormal mitosis	"anomaly in the process of cell division including both division of the nucleus (karyokinesis) and the cytoplasm (cytokinesis) " [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Cdk5rap2^an/Cdk5rap2^an,Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: WBB6F1
MP:0004367	abnormal strial intermediate cells	"any structural abnormality in the melanocytes known to migrate from the neural crest during ontogeny to become located between the epithelial marginal cell layer and the mesodermal basal cell layer within the intrastrial space; the predominant cellular component of the electrogenic machinery that generates an endocochlear potential (80-100 mV)" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: Not Specified
MP:0004411	decreased endocochlear potential	"reduction of the electrical potential difference between the endolymphatic and perilymphatic compartments of the cochlea" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: Not Specified Allelic Composition: Tyrp1^B-lt/Tyrp1⁺ Genetic Background: Not Specified
MP:0004924	abnormal behavior	"anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Tyrp1^b-1FCHLc/Tyrp1^b-1FCHLc Genetic Background: involves: 101/Rl * C3H/Rl
MP:0005071	enlarged melanin granules in hair follicle	"increased size of the pigment particles in the hair follicle" [J:5078]	Show Allelic Composition: Gria4^tm1Dgen/Gria4^tm1Dgen Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
MP:0005072	abnormal hair follicle melanin granule	"anomalous pigment paricles in the hair follicles" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Gria4^tm1Dgen/Gria4^tm1Dgen Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
MP:0005075	abnormal melanosome morphology	"anomalous structure of these tissue-specific cytoplasmic organelles within which melanin pigments are synthesized and stored" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:5346]	Show Allelic Composition: a/a,Tyrp1^b/Tyrp1^b Genetic Background: involves: C57BL/6J
MP:0005102	abnormal iris pigmentation	"anomalous coloring of the adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Rb1^tm2Brn/Rb1^tm2Brn,Tg(Pcp2-cre)756Mro/0 Genetic Background: involves: 129P2/OlaHsd * FVB Allelic Composition: Gpnmb^R150X/Gpnmb^R150X,Tyrp1^b/Tyrp1^b Genetic Background: B6.D2-Tyrp1^b Gpnmb^R150X
MP:0005114	premature hair loss	"release of fur at an earlier than expected time" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Lyst^bg-slt/Lyst^bg-slt,Myo5a^d/Myo5a^d,Oca2^p/Oca2^p,Tyrp1^b/Tyrp1^b Genetic Background: involves: CT/Ch * YZ57/Ch
MP:0005172	lack of eye pigmentation	"visual organs are devoid of coloring pigment in relation to control animals, usually resulting in a red or pink color" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500]	Show Allelic Composition: Mertk^tm1Grl/Mertk^tm1Grl,Tyro3^tm1Grl/Tyro3^tm1Grl Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Tyrp1^b/Tyrp1^b-11PU Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-11R30M Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-12PU Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-13DT Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-13R75M Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-173G Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-1DFiOD Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-1ETOPc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-1FBleo Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-1FCHLc/Tyrp1^b-1FCHLc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-1FCHLc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-1MLP5/Tyrp1^b-1MLP5 Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-1MLP5 Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-1OZ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-1THO-IV Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-26R60L Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-2MLP10/Tyrp1^b-2MLP10 Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-2MLP10 Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-2MLP7.5/Tyrp1^b-2MLP7.5 Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-2MLP7.5 Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-331K Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-33G Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-37DTD Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-37FrThc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-37Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-3CHLe Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-3MLPc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-3YPSc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-3YPSh Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-46UThc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-47DThWb Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-49HATh Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-4ACRg Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-51DThWb Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-55CoS Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-5CHLe Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-5CHLo/Tyrp1^b-5CHLo Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-5CHLo Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-5MLPm Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-5FBleb Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-8PUb Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-9Bleo Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-9PU Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b/Tyrp1^b-9R75VH Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^B-w/Tyrp1^b Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^B-w/Tyrp1^B-w Genetic Background: involves: 101/Rl * C3H/Rl
MP:0005199	abnormal iris pigment epithelium	"anomaly in the epithelial layer of the iris composed of cells containing pigment granules " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Hoxa11^tm1Ssp/Hoxa11^tm1Ssp,Hoxd^tm3Ddu/Hoxd^tm3Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL Allelic Composition: Gpnmb^R150X/Gpnmb^R150X,Tyrp1^isa/Tyrp1^isa Genetic Background: involves: C57BL/6J * DBA/2J
MP:0005208	abnormal iris stroma morphology	"structural anomaly of the lamellated connective tissue of the iris" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Hoxa11^tm1Ssp/Hoxa11^tm1Ssp,Hoxd^tm3Ddu/Hoxd^tm3Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL Allelic Composition: Tyrp1^isa/Tyrp1^isa Genetic Background: DBA/2J Allelic Composition: Tyrp1^isa/Tyrp1^isa Genetic Background: involves: C57BL/6J * DBA/2J Allelic Composition: Gpnmb^R150X/Gpnmb^R150X,Tyrp1^isa/Tyrp1^isa Genetic Background: involves: C57BL/6J * DBA/2J
MP:0005257	abnormal intraocular pressure	"anomaly in the amount of force per unit area exerted by the intraocular fluid within the eye" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Gpnmb^R150X/Gpnmb^R150X,Tyrp1^b/Tyrp1^b Genetic Background: B6.D2-Tyrp1^b Gpnmb^R150X
MP:0005606	increased bleeding time	"greater than the normal duration of blood flow after skin puncture; indicative of platelet and capillary function" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]	Show Allelic Composition: Hras^tm1Xbr/Hras^tm1Xbr Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0005607	decreased bleeding time	"less than the normal duration of blood flow after skin puncture; indicative of platement and capillary function" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]	Show Allelic Composition: Mib1^tm1Kong/Mib1^tm1Kong Genetic Background: involves: 129P2/OlaHsd
MP:0006228	iris atrophy	"wasting of the iris" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Gpnmb^R150X/Gpnmb^R150X Genetic Background: B6.D2-Gpnmb^R150X Allelic Composition: Gpnmb^R150X/Gpnmb^R150X,Tyrp1^b/Tyrp1^b Genetic Background: B6.D2-Tyrp1^b Gpnmb^R150X
MP:0008067	retinal ganglion cell degeneration	"degeneration or loss of ganglion neurons located in the innermost nuclear layer of the retina of that receive visual information from photoreceptors via various intermediate cells such as bipolar cells, amacrine cells, and horizontal cells; axons from these cells form the optic nerve and connect mainly to the lateral geniculate nucleus (LGN) and to the suprachiasmatic nucleus in the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Hoxa11^tm1Ssp/Hoxa11^tm1Ssp,Hoxd^tm3Ddu/Hoxd^tm3Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL Allelic Composition: Gpnmb^R150X/Gpnmb^R150X,Tyrp1^isa/Tyrp1^isa Genetic Background: involves: C57BL/6J * DBA/2J
MP:0008238	abnormal dorsoventral coat patterning	"irregular or unusual pigmentation pattern of the dorsal-to-ventral axis compared to control animals" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: a/a,Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: Not Specified Allelic Composition: a/a,Tyrp1^B-lt/Tyrp1⁺ Genetic Background: Not Specified
MP:0008731	abnormal hair shaft melanin granules	"any amount or distribution anomaly of pigment polymers in the hair shaft" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: a/a,Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: Not Specified Allelic Composition: a/a,Tyrp1^B-lt/Tyrp1⁺ Genetic Background: Not Specified
MP:0008732	reduced hair shaft melanin granule number	"the number of pigment polymers in the hair shaft is less than normal" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: a/a,Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: Not Specified Allelic Composition: a/a,Tyrp1^B-lt/Tyrp1⁺ Genetic Background: Not Specified
MP:0008733	abnormal hair shaft melanin granule distribution	"disruption in the regular arrangement of pigment polymers in the hair shaft" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: a/a,Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: Not Specified Allelic Composition: a/a,Tyrp1^B-lt/Tyrp1⁺ Genetic Background: Not Specified
MP:0009321	histiocytic sarcoma		Show Allelic Composition: Cdk5rap2^an/Cdk5rap2^an,Tyrp1^B-lt/Tyrp1^B-lt Genetic Background: WBB6F1
MP:0010192	abnormal retinal melanin granule morphology	"any structural anomaly of the pigment particles in the retina" [ISBN-13:978-1-4051-2034-0 "The Pigmentary System, Second Edition"]	Show Allelic Composition: a/a,Lyst^bg/Lyst^bg,Tyrp1^b/Tyrp1^b Genetic Background: involves: C3H/Rl * C57BL/6J
MP:0010193	abnormal choroid melanin granule morphology	"any structural anomaly of the pigment particles in the choroid" [ISBN-13:978-1-4051-2034-0 "The Pigmentary System, Second Edition"]	Show Allelic Composition: a/a,Lyst^bg/Lyst^bg,Tyrp1^b/Tyrp1^b Genetic Background: involves: C3H/Rl * C57BL/6J
MP:0011089	complete perinatal lethality	"death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]	Show Allelic Composition: Tyrp1^b/Tyrp1^b-1OZ Genetic Background: involves: 101/Rl * C3H/Rl
MP:0011091	complete prenatal lethality	"death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]	Show Allelic Composition: Krt71^Ca-Rin/? Genetic Background: C57BL/6Slc-Krt71^Ca-Rin Allelic Composition: Tyrp1^b-11R30M/Tyrp1^b-11R30M Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-12PU/Tyrp1^b-12PU Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-13DT/Tyrp1^b-13DT Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-13R75M/Tyrp1^b-13R75M Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-173G/Tyrp1^b-173G Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-1DFiOD/Tyrp1^b-1DFiOD Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-1ETOPc/Tyrp1^b-1ETOPc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-1FBleo/Tyrp1^b-1FBleo Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-1THO-IV/Tyrp1^b-1THO-IV Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-26R60L/Tyrp1^b-26R60L Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-331K/Tyrp1^b-331K Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-33G/Tyrp1^b-33G Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-37DTD/Tyrp1^b-37DTD Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-37FrThc/Tyrp1^b-37FrThc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-37Pub/Tyrp1^b-37Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-3CHLe/Tyrp1^b-3CHLe Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-3MLPc/Tyrp1^b-3MLPc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-3YPSc/Tyrp1^b-3YPSc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-3YPSh/Tyrp1^b-3YPSh Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-46UThc/Tyrp1^b-46UThc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-47DThWb/Tyrp1^b-47DThWb Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-49HATh/Tyrp1^b-49HATh Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-4ACRg/Tyrp1^b-4ACRg Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-51DThWb/Tyrp1^b-51DThWb Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-55CoS/Tyrp1^b-55CoS Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-5CHLe/Tyrp1^b-5CHLe Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-5MLPm/Tyrp1^b-5MLPm Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-8PUb/Tyrp1^b-8PUb Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-9Bleo/Tyrp1^b-9Bleo Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-9PU/Tyrp1^b-9PU Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Tyrp1^b-9R75VH/Tyrp1^b-9R75VH Genetic Background: involves: 101/Rl * C3H/Rl
MP:0011277	decreased tail pigmentation	"visually detectable dilution of pigment present on the tail surface" [MGI:csmith]	Show Allelic Composition: A/?,Lyst^bg/Lyst^bg,Tyrp1⁺/? Genetic Background: Not Specified
MP:0011279	decreased ear pigmentation	"visually detectable dilution of pigment present in the outer ear" [MGI:csmith]	Show Allelic Composition: A/?,Lyst^bg/Lyst^bg,Tyrp1⁺/? Genetic Background: Not Specified

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