ENSMUSG00000010825


Mus musculus

Features
Gene ID: ENSMUSG00000010825
  
Biological name :Grid2ip
  
Synonyms : Grid2ip / Mus musculus glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1 (Grid2ip), transcript variant 3, mRNA. / Q0QWG9
  
Possible biological names infered from orthology : A4D2P6 / Grid2 interacting protein
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: G2
Gene start: 143357338
Gene end: 143392152
  
Corresponding Affymetrix probe sets: 10527186 (MoGene1.0st)   1450310_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000010969
Ensembl peptide - ENSMUSP00000106361
Ensembl peptide - ENSMUSP00000113443
NCBI entrez gene - 170935     See in Manteia.
MGI - MGI:2176213
RefSeq - XM_006504650
RefSeq - NM_001159321
RefSeq - NM_001347529
RefSeq - NM_133355
RefSeq Peptide - NP_001334458
RefSeq Peptide - NP_579933
RefSeq Peptide - NP_001152793
swissprot - Q0QWG9
Ensembl - ENSMUSG00000010825
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 grid2ipaENSDARG00000076103Danio rerio
 Q6ZM86ENSDARG00000095603Danio rerio
 ENSGALG00000040720Gallus gallus
 A4D2P6ENSG00000215045Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fhod3 / Q76LL6 / FH1/FH2 domain-containing protein 3 / Q2V2M9* / formin homology 2 domain containing 3*ENSMUSG0000003429517
Fmn2 / Q9JL04 / Formin-2 / Q9NZ56*ENSMUSG0000002835416
Fmn1 / Q05860 / Formin-1 / Q68DA7*ENSMUSG0000004404216
Fhod1 / Q6P9Q4 / FH1/FH2 domain-containing protein 1 / Q9Y613* / formin homology 2 domain containing 1*ENSMUSG0000001477813


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR015425  Formin, FH2 domain
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007216 G-protein coupled glutamate receptor signaling pathway TAS
 biological_processGO:0030036 actin cytoskeleton organization TAS
 biological_processGO:0060292 long term synaptic depression IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043197 dendritic spine IDA
 cellular_componentGO:0045202 synapse IDA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001898 abnormal long term depression "change from the normal, persistent activity-dependent decrease in synaptic efficacy between neurons, often following slow, weak stimulation of neurons" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Principles of Neural Science:ISBN 0-8385-8034-3]
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Allelic Composition: Fzd5tm1Nat/Fzd5tm2Nat,Gt(ROSA)26Sortm1(cre/ERT)Nat/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL

 MP:0001961 abnormal reflex "anomalies in an involuntary response to a peripheral stimulus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Fzd5tm1Nat/Fzd5tm2Nat,Gt(ROSA)26Sortm1(cre/ERT)Nat/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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