ENSMUSG00000015355


Mus musculus

Features
Gene ID: ENSMUSG00000015355
  
Biological name :Cd48
  
Synonyms : Cd48 / CD48 antigen / P18181
  
Possible biological names infered from orthology : CD48 molecule / P09326
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: H3
Gene start: 171682009
Gene end: 171705258
  
Corresponding Affymetrix probe sets: 10351658 (MoGene1.0st)   1427301_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000015499
Ensembl peptide - ENSMUSP00000064241
NCBI entrez gene - 12506     See in Manteia.
MGI - MGI:88339
RefSeq - NM_007649
RefSeq Peptide - NP_031675
swissprot - F8WHM0
swissprot - P18181
Ensembl - ENSMUSG00000015355
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CD48ENSGALG00000035856Gallus gallus
 CD48ENSG00000117091Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR033548  CD48 antigen
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002819 regulation of adaptive immune response IEA
 biological_processGO:0007165 signal transduction IDA
 biological_processGO:0042110 T cell activation IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0045121 membrane raft ISO
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001828 abnormal T cell activation "anomaly in the process of producing effector T cells from naive T cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
Genetic Background: involves: 129/Sv * CD-1 * STOCK EdaTa

 MP:0005095 decreased T cell proliferation "reduced clonal expansion of naive T cells in response to stimuli" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
Genetic Background: involves: 129/Sv * CD-1 * STOCK EdaTa

 MP:0008074 increased CD4-positive T cell number "greater number of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
Genetic Background: involves: 129/Sv * CD-1 * STOCK EdaTa

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000004709 Cd244 / Q07763 / Natural killer cell receptor 2B4 / Q9BZW8* / CD244 molecule*  / complex / reaction






 

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