ENSMUSG00000019432


Mus musculus

Features
Gene ID: ENSMUSG00000019432
  
Biological name :Ddx39b
  
Synonyms : Ddx39b / Q9Z1N5 / Spliceosome RNA helicase Ddx39b
  
Possible biological names infered from orthology : DExD-box helicase 39B / Q13838
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: B1
Gene start: 35241746
Gene end: 35253707
  
Corresponding Affymetrix probe sets: 10444761 (MoGene1.0st)   1437367_at (Mouse Genome 430 2.0 Array)   1437984_x_at (Mouse Genome 430 2.0 Array)   1447779_x_at (Mouse Genome 430 2.0 Array)   1448221_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000070682
Ensembl peptide - ENSMUSP00000133428
Ensembl peptide - ENSMUSP00000133705
Ensembl peptide - ENSMUSP00000134178
NCBI entrez gene - 53817     See in Manteia.
MGI - MGI:99240
RefSeq - NM_001252457
RefSeq - NM_019693
RefSeq Peptide - NP_001239386
RefSeq Peptide - NP_062667
swissprot - G3UXI6
swissprot - Q9Z1N5
Ensembl - ENSMUSG00000019432
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DDX39BENSG00000198563Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ddx39 / Q8VDW0 / ATP-dependent RNA helicase DDX39A / DDX39A* / O00148* / DExD-box helicase 39A*ENSMUSG0000000548191
Ddx20 / Q9JJY4 / Probable ATP-dependent RNA helicase DDX20 / Q9UHI6* / DEAD-box helicase 20*ENSMUSG0000002790532


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000245 spliceosomal complex assembly ISO
 biological_processGO:0000398 mRNA splicing, via spliceosome ISO
 biological_processGO:0001889 liver development IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006406 mRNA export from nucleus IBA
 biological_processGO:0006974 cellular response to DNA damage stimulus IBA
 biological_processGO:0008380 RNA splicing ISO
 biological_processGO:0010468 regulation of gene expression IBA
 biological_processGO:0010501 RNA secondary structure unwinding ISO
 biological_processGO:0032786 positive regulation of DNA-templated transcription, elongation ISS
 biological_processGO:0045727 positive regulation of translation IEA
 biological_processGO:0046784 viral mRNA export from host cell nucleus ISO
 biological_processGO:0051028 mRNA transport IEA
 biological_processGO:0061051 positive regulation of cell growth involved in cardiac muscle cell development IEA
 biological_processGO:1904707 positive regulation of vascular smooth muscle cell proliferation IEA
 biological_processGO:2000002 negative regulation of DNA damage checkpoint ISO
 biological_processGO:2000573 positive regulation of DNA biosynthetic process IEA
 cellular_componentGO:0000346 transcription export complex ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005681 spliceosomal complex ISO
 cellular_componentGO:0005687 U4 snRNP ISO
 cellular_componentGO:0005688 U6 snRNP ISO
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016363 nuclear matrix IEA
 cellular_componentGO:0016607 nuclear speck ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity ISO
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008186 RNA-dependent ATPase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity ISO
 molecular_functionGO:0017070 U6 snRNA binding ISO
 molecular_functionGO:0030621 U4 snRNA binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0043008 ATP-dependent protein binding ISO


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA 3-end processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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