ENSMUSG00000019944


Mus musculus
gtpaseRhobtb1smalldomainsuperfamilybindingbtbpozrhoproteintypegtp-bindingskpp-loopcontainingnucleosidetriphosphatehydrolasemediatedsignaltransductioncellularcomponentintracellularnucleotideactivitygtpcycle

Features
Gene ID: ENSMUSG00000019944
  
Biological name :Rhobtb1
  
Synonyms : Q9DAK3 / Rhobtb1 / Rho-related BTB domain-containing protein 1
  
Possible biological names infered from orthology : O94844 / Rho related BTB domain containing 1
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: B5.3
Gene start: 69151434
Gene end: 69291791
  
Corresponding Affymetrix probe sets: 10363773 (MoGene1.0st)   1429206_at (Mouse Genome 430 2.0 Array)   1429656_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000128667
Ensembl peptide - ENSMUSP00000128356
Ensembl peptide - ENSMUSP00000129119
Ensembl peptide - ENSMUSP00000132068
Ensembl peptide - ENSMUSP00000131509
Ensembl peptide - ENSMUSP00000131313
Ensembl peptide - ENSMUSP00000131222
Ensembl peptide - ENSMUSP00000020101
Ensembl peptide - ENSMUSP00000065095
Ensembl peptide - ENSMUSP00000127904
NCBI entrez gene - 69288     See in Manteia.
MGI - MGI:1916538
RefSeq - XM_011243553
RefSeq - NM_001081347
RefSeq - NM_001252636
RefSeq - NM_001252637
RefSeq - NM_001252638
RefSeq - XM_006514048
RefSeq - XM_006514049
RefSeq - XM_006514051
RefSeq - XM_006514052
RefSeq - XM_006514053
RefSeq - XM_006514054
RefSeq Peptide - NP_001239566
RefSeq Peptide - NP_001239567
RefSeq Peptide - NP_001239565
RefSeq Peptide - NP_001074816
swissprot - E9PZ72
swissprot - F6UIH6
swissprot - E9PZ17
swissprot - Q9DAK3
swissprot - E9PYH9
swissprot - E9QAZ7
swissprot - E9Q922
swissprot - E9Q1X7
Ensembl - ENSMUSG00000019944
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rhobtb1ENSDARG00000079468Danio rerio
 RHOBTB1ENSGALG00000003073Gallus gallus
 O94844ENSG00000072422Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q91V93 / Rhobtb2 / Rho-related BTB domain-containing protein 2 / Q9BYZ6* / Rho related BTB domain containing 2*ENSMUSG0000002207568
Rac1 / P63001 / RAS-related C3 botulinum substrate 1 / P63000* / Rac family small GTPase 1*ENSMUSG0000000184712
Rac3 / P60764 / RAS-related C3 botulinum substrate 3 / P60763* / Rac family small GTPase 3*ENSMUSG0000001801212
Cdc42 / P60766 / Cell division control ENSMUSG0000000669911
Rhoq / Q8R527 / Rho-related GTP-binding protein RhoQ / P17081* / ras homolog family member Q*ENSMUSG0000002414311
Rac2 / Q05144 / Ras-related C3 botulinum toxin substrate 2 / P15153* / Rac family small GTPase 2*ENSMUSG0000003322011
Rhog / P84096 / ras homolog family member G / P84095*ENSMUSG0000007398211
Rhov / Q8VDU1 / Rho-related GTP-binding protein RhoV / Q96L33* / ras homolog family member V*ENSMUSG0000003422610
Rhou / Q9EQT3 / Rho-related GTP-binding protein RhoU / Q7L0Q8* / ras homolog family member U*ENSMUSG0000003996010
Rhoj / Q9ER71 / ras homolog family member J / Q9H4E5*ENSMUSG0000004676810


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR001806  Small GTPase superfamily
 IPR003578  Small GTPase superfamily, Rho type
 IPR005225  Small GTP-binding protein domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
cell communicationcellular response to stimuluscell communicationcellular response to stimuluscell communicationcellular response to stimuluscell communicationcellular response to stimuluscell communicationcellular response to stimuluscell communicationcellular response to stimuluscell communicationcellular response to stimuluscell communicationcellular response to stimuluscell communicationcellular response to stimuluscell communicationcellular response to stimuluscell communicationcell communicationcellular response to stimuluscellular response to stimulus
organic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compoorganic cyclic compound bindingheterocyclic compounheterocyclic compound bindingsmall molecule bindismall molecule bindinghydrolase activityhydrolase activityprotein bindingprotein bindingion bindingion bindingcarbohydrate derivatcarbohydrate derivative binding
cellcellcellcellcellcellcellcellcellcellcellcell
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr