ENSMUSG00000020409


Mus musculus

Features
Gene ID: ENSMUSG00000020409
  
Biological name :Slu7
  
Synonyms : Pre-mRNA-splicing factor SLU7 / Q8BHJ9 / Slu7
  
Possible biological names infered from orthology : O95391 / SLU7 homolog, splicing factor
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B1.1
Gene start: 43433744
Gene end: 43447981
  
Corresponding Affymetrix probe sets: 10375290 (MoGene1.0st)   1420030_at (Mouse Genome 430 2.0 Array)   1425487_at (Mouse Genome 430 2.0 Array)   1425488_at (Mouse Genome 430 2.0 Array)   1425489_at (Mouse Genome 430 2.0 Array)   1447146_s_at (Mouse Genome 430 2.0 Array)   1447805_s_at (Mouse Genome 430 2.0 Array)   1451727_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020681
Ensembl peptide - ENSMUSP00000116609
Ensembl peptide - ENSMUSP00000122142
Ensembl peptide - ENSMUSP00000137281
NCBI entrez gene - 193116     See in Manteia.
MGI - MGI:2385598
RefSeq - NM_148673
RefSeq - NM_198936
RefSeq - XM_011248823
RefSeq Peptide - NP_683514
RefSeq Peptide - NP_945174
swissprot - Q8BHJ9
swissprot - B0QZT9
swissprot - Z4YM25
Ensembl - ENSMUSG00000020409
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slu7ENSDARG00000038870Danio rerio
 SLU7ENSGALG00000034414Gallus gallus
 SLU7ENSG00000164609Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR021715  Pre-mRNA splicing Prp18-interacting factor
 IPR036875  Zinc finger, CCHC-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000375 RNA splicing, via transesterification reactions ISS
 biological_processGO:0000380 alternative mRNA splicing, via spliceosome ISS
 biological_processGO:0000389 mRNA 3"-splice site recognition ISO
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006886 intracellular protein transport ISO
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0034605 cellular response to heat ISS
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005681 spliceosomal complex ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0016607 nuclear speck ISS
 cellular_componentGO:0030532 small nuclear ribonucleoprotein complex ISS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 cellular_componentGO:0071013 catalytic step 2 spliceosome ISO
 molecular_functionGO:0000386 second spliceosomal transesterification activity ISO
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0008270 zinc ion binding ISS
 molecular_functionGO:0030628 pre-mRNA 3"-splice site binding ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA 3-end processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000221 decreased WBC count "fewer than normal numbers of WBCs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0000222 decreased neutrophil count "fewer than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0000223 decreased monocyte count "fewer than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0000416 sparse fur "fur that is significantly less dense" [J:46854]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0013023 decreased Ly6C high monocyte number "decrease in the number of monocytes that express high levels of Ly6C and low MHC class II that represent a subset of circulating inflammatory monocytes that are recruited to infected or inflamed tissues" [MGI:Annie_Speak]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0013026 decreased Ly6C low monocyte number "decrease in the number of monocytes that express low levels of Ly6C and low MHC class II that represent a subset of patrolling monocytes" [MGI:Annie_Speak]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr