ENSMUSG00000021417


Mus musculus

Features
Gene ID: ENSMUSG00000021417
  
Biological name :Eci2
  
Synonyms : Eci2 / Enoyl-CoA delta isomerase 2, mitochondrial / Q9WUR2
  
Possible biological names infered from orthology : enoyl-CoA delta isomerase 2 / O75521
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: A3.3
Gene start: 34977748
Gene end: 35027096
  
Corresponding Affymetrix probe sets: 10408656 (MoGene1.0st)   1431012_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000129164
Ensembl peptide - ENSMUSP00000137411
Ensembl peptide - ENSMUSP00000131735
Ensembl peptide - ENSMUSP00000130283
Ensembl peptide - ENSMUSP00000130076
Ensembl peptide - ENSMUSP00000129477
Ensembl peptide - ENSMUSP00000129428
Ensembl peptide - ENSMUSP00000021854
Ensembl peptide - ENSMUSP00000105880
Ensembl peptide - ENSMUSP00000126500
NCBI entrez gene - 23986     See in Manteia.
MGI - MGI:1346064
RefSeq - XM_006516677
RefSeq - XM_006516676
RefSeq - XM_006516675
RefSeq - XM_006516674
RefSeq - XM_006516673
RefSeq - NM_011868
RefSeq - NM_001110331
RefSeq Peptide - NP_001103801
RefSeq Peptide - NP_035998
swissprot - E9Q7A8
swissprot - Q3TCD4
swissprot - Q9WUR2
swissprot - E9PUY9
swissprot - E9PVM6
swissprot - E9PYA9
swissprot - E9PYC6
swissprot - E9Q858
Ensembl - ENSMUSG00000021417
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eci2ENSDARG00000102412Danio rerio
 ECI2ENSGALG00000012809Gallus gallus
 ECI2ENSG00000198721Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Eci3 / Q78JN3 / Enoyl-CoA delta isomerase 3, peroxisomal / ECI2* / O75521* / enoyl-CoA delta isomerase 2*ENSMUSG0000002141664
Cdyl2 / Q9D5D8 / Chromodomain Y-like protein 2 / Q8N8U2* / chromodomain Y like 2*ENSMUSG0000003175830
Cdyl / Q9WTK2 / Chromodomain Y-like protein / Q9Y232* / chromodomain Y like*ENSMUSG0000005928830
Echs1 / Q8BH95 / Enoyl-CoA hydratase, mitochondrial / P30084* / enoyl-CoA hydratase, short chain 1*ENSMUSG0000002546518
Auh / AU RNA binding methylglutaconyl-CoA hydratase / Q13825*ENSMUSG0000002146017
Echdc2 / Q3TLP5 / Enoyl-CoA hydratase domain-containing protein 2, mitochondrial / Q86YB7* / enoyl-CoA hydratase domain containing 2*ENSMUSG0000002860116
Echdc3 / Q9D7J9 / Enoyl-CoA hydratase domain-containing protein 3, mitochondrial / Q96DC8* / enoyl-CoA hydratase domain containing 3*ENSMUSG0000003906316
Ech1 / O35459 / Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial / Q13011* / enoyl-CoA hydratase 1*ENSMUSG0000005389815


Protein motifs (from Interpro)
Interpro ID Name
 IPR000582  Acyl-CoA-binding protein, ACBP
 IPR001753  Enoyl-CoA hydratase/isomerase
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR014748  Enoyl-CoA hydratase, C-terminal
 IPR022408  Acyl-CoA-binding protein, ACBP, conserved site
 IPR029045  ClpP/crotonase-like domain superfamily
 IPR035984  Acyl-CoA binding protein superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006635 fatty acid beta-oxidation IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009062 fatty acid catabolic process ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005777 peroxisome ISO
 cellular_componentGO:0005782 peroxisomal matrix IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 molecular_functionGO:0000062 fatty-acyl-CoA binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004165 dodecenoyl-CoA delta-isomerase activity ISO
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds IEA


Pathways (from Reactome)
Pathway description
Beta-oxidation of very long chain fatty acids
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000021416 Eci3 / Q78JN3 / Enoyl-CoA delta isomerase 3, peroxisomal / ECI2* / O75521* / enoyl-CoA delta isomerase 2*  / complex
 ENSMUSG00000021417 Eci2 / Q9WUR2 / Enoyl-CoA delta isomerase 2, mitochondrial / O75521* / enoyl-CoA delta isomerase 2*  / complex






 

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